Prostate Cancer: A Targeted Diagnosis

Fusing Two Tools for an Accurate Diagnosis:
MR/Ultrasound Fusion Biopsy
for a Targeted Diagnosis of Prostate Cancer

MR/ultrasound fusion biopsy is a powerful diagnostic tool for the analysis, planning, and targeted biopsy of the prostate.

An MRI pre-biopsy scan is an important tool in diagnosing prostate.
So is an ultrasound-guided biopsy image.

Combining them
creates a more accurate way to locate tumors.


It is a complete clinical MR (magnetic resonance) solution that offers a truly new biopsy option for many patients with elevated and/or rising PSA (prostate-specific antigen) levels. It may effectively detect tumors in men with prior negative biopsies but persistently elevated PSA levels.

Biopsies are mapped, targeted, and tracked.

The technology fuses pre-biopsy MR images of the prostate with ultrasound-guided biopsy images in real time to create a detailed, three-dimensional view of the prostate.

The process typically involves a 20-minute procedure done in an outpatient setting under local anesthesia. The result is excellent delineation of the prostate as well as suspicious lesions.

Fusion Biopsy compared to a Traditional Biopsy

Fox Chase Cancer Center and Temple University Hospital were the first two sites in the area to offer targeted MR/ultrasound fusion biopsy.

This innovative technology may result in fewer needle biopsies and better treatment decisions for patients with prostate cancer.


In a traditional core needle biopsy, urologists use a fine needle to collect a number of tissue samples from the prostate gland, which are then examined for cell abnormalities that are a sign of prostate cancer.

Whereas the traditional method lacks precision and uses random prostate sampling, MR/ultrasound fusion biopsy helps urologists to avoid missing hard-to-find, yet often aggressive prostate cancer. It potentially minimizes the overdiagnosis of non-aggressive cancers, while maximizing the likelihood of detecting aggressive tumors.

Biopsies guided by MR/ultrasound fusion enable both physicians and patients to make more informed decisions ranging from prostate cancer diagnosis to treatment options—such as active surveillance or more radical interventions.

Learn more about becoming a candidate
for a Uronav fusion biospy »

Other Tools Used To Diagnose Prostate Cancer

Fox Chase offers a full range of diagnostic tools. In addition, Fox Chase diagnostic physicians are experienced at accurately interpreting the results.

  • Digital Rectal Exam (DRE)
  • PSA Test
  • "Percentage-free" PSA Test
  • Prostate Biopsy and Transrectal Ultrasound (TRUS)
  • Gleason Grading System After a Biopsy

Read about other diagnostic tools available for prostate cancer »

The Core Needle Biopsy for Prostate Cancer Diagnosis

A core needle biopsy is the main method used to diagnose prostate cancer. It takes just a few minutes to perform and may produce some temporary discomfort.

In this procedure, a sample of tissue is removed and then examined under a microscope. The doctor inserts several narrow needles (usually through the wall of the rectum) into the prostate gland, using transrectal ultrasound (TRUS) to guide the needles to the prostate. Each needle then removes a cylinder of tissue, or core, usually about 1/2-inch long and 1/16-inch across. The tissue samples are sent to the laboratory where a pathologist checks the tissue under a microscope to see if cancer is present. If cancer is present, the pathologist will also assign it a Gleason grade.


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See National Cancer Institute information on Prostate Cancer
Prostate Cancer Risk Assessment Program

For men who have a family history or other risk factors for prostate cancer. Learn more »
Cancer diagnosis information for patients from the College of American Pathologists