Clinical Expertise:
Colorectal cancer, gastric cancer, hepatobiliary cancer, sarcomas, melanomas, minimally invasive surgery, and isolated limb infusion for in-transit melanoma and extremity sarcomas.
Certifications:
American Board of Surgery,
January 30, 2008
It is an honor to join the staff of the Fox Chase Cancer Center. My initial exposure during medical school at Fox Chase led me down the path of Surgical Oncology. As a native Philadelphian, I am privileged to work at such an esteemed institution. I was enthralled then by the dedicated care of the staff in dealing with all aspects of treating patients diagnosed with cancer, and I hope to continue this throughout my career at Fox Chase.
During my fellowship at the National Cancer Institute in Bethesda, Maryland, I learned from experts in the field of surgical oncology about clinical trial design, experimental therapeutics and the importance of bench-to-bedside research to progress the fight against cancer. I encountered patients with very complex problems, and the greatest lesson I learned was there are always treatment options, utilizing all different types of techniques including radiation, chemotherapy and surgery.
My clinical surgical oncology fellowship at the Moffitt Cancer Center in Tampa, Florida has provided me with an extensive understanding of the multidisciplinary approach to treating patients with cancer. One of the greatest benefits of a cancer center like Fox Chase is the close knit group of expert physicians from all specialties that are constantly interacting and providing the highest level of care using the most innovative strategies to treat all aspects of cancer. I have developed a particularly strong interest in the surgical and multimodal treatment of patients with gastrointestinal and soft tissue malignancies (including melanoma and sarcoma), using traditional surgery, regional therapies, and minimally invasive techniques. I have the surgical skills to perform many of these complex procedures using laparoscopic or robotic techniques and have had training in using in using the newest techniques. I am an expert in the treatment of colorectal cancer including; sphincter sparing and nerve sparing resections, and treating patients with hereditary colorectal cancer syndromes.
Single Incision Laparoscopic Surgery — a First at Fox Chase
I performed one of the first SILS (single incision laparoscopic surgery) colectomies at Fox Chase and in the region and have continued to use this technique for both colon resections and other types of procedures. This makes Fox Chase one of the only hospitals in the region that provides Single Incision Laparoscopic Surgery (SILS) for patients undergoing colon removal.
Most importantly, I hold my patients as my number one priority. I will spend as much time as necessary educating, answering questions and providing guidance for each individual patient to help them throughout each stage of treatment. I believe in candid discussions, where both the patients and families goals and expectations are openly communicated. We will work together as a team to formulate a treatment plan. My personal goal is to treat and care for every patient with the same compassion and honesty as if they were a friend or family member.
Medical Education
MD, Temple University School of Medicine, Philadelphia, PA, 2000
Residencies
Chief Resident, Temple University School of Medicine, Philadelphia, PA, 2005;
Resident, Temple University School of Medicine, Philadelphia, PA, 2003
Research Interests
Outcomes studies in gastrointestinal and cutaneous malignancies. Regional therapies in the treatment of cancer.
Publications
Search Dr. Farma's publications on PubMed
Peer-Reviewed Publications:
- Farma J, Leeser D, Furukawa S, Dempsey DT. Laparoscopic Repair of Diaphragmatic Hernia after Left Ventricular Assist Device. Journal of Laparoendoscopic & Advanced Surgical Techniques, Vol. 13(3): 185-9. June 2003.
- Goldberg M, Farma J, Lampert C, Colarusso P, Coia L, Frucht H, Goosenberg E, Beard M, Weiner LM. Survival Following Intensive Preoperative Combined Modality Therapy with Paclitaxel, Cisplatin, 5-Fluorouracil and Radiation in Resectable Esophageal Carcinoma – A Phase I Report. J Thorac Cardiovasc Surg, 126(4): 1168-73. October 2003.
- Farma J, Nguyen D. Cardiac Tamponade. Postgrad Med J. 81(951): 67. January 2005.
- Berger AC, Farma J, Scott WJ, Freedman G, Weiner L, Cheng JD, Wang H, Goldberg M. Complete Response to Neoadjuvant Chemoradiotherapy in Esophageal Carcinoma is Associated with Significantly Improved Survival. J Clin Oncol, 23(19): 4330-7. March 2005.
- Puhlmann M, Weinreich DM, Farma JM, Carroll NM, Turner EM, Alexander HR Jr. Interleukin-1beta Induced Vascular Permeability is Dependent on Induction of Endothelial Tissue Factor (TF) Activity. J Transl Med. 3:37. September 2005.
- Farma JM, Pingpank JF, Libutti SK, Bartlett DL, Ohl S, Beresneva T, Alexander HR Jr. Limited Survival in Patients with Carcinomatosis from Foregut Malignancies after Cytoreduction and Continuous Hyperthermic Peritoneal Perfusion. J Gastrointest Surg. 9(9): 1346-1353. December 2005.
- Farma JM, Hoffman JP. Non-neoplastic Celiac Axis Occlusion in Patients Undergoing Pancreaticoduodenectomy. Am J Surg. 193(3): 341-4. March 2007.
- Farma JM, Mohiuddin, J, Grewal H. A Pneumonia That Will Not Go Away. Contemporary Surgery. 63(4). April 2007.
- Farma JM, Puhlmann M, Cox D, Soriano, PA, Paciotti GF, Tamarkin L, Alexander HR. Direct Evidence for Rapid and Selective Induction of Tumor Neovascular Permeability by Tumor Necrosis Factor and a Novel Derivative, Colloidal Gold Bound Tumor Necrosis Factor. Int J Cancer. 120(11): 2474-80. June 2007.
- Zager JS, Bui MM, Farma JM, Messina JL, Sondak VK. Proper Margins of Excision in Dermatofibrosarcoma Protuberans: Wide or Narrow? Ann Surg Oncol. May 2008.
- Farma JM, Santillan AA, Melis M, Walters J, Belinc D, Chen D, Eikman, E, Malafa M. PET/CT Fusion Scan Enhances CT Staging in Patients with Pancreatic Neoplasms. Ann Surg Oncol. June 2008.
- Santillan AA, Farma JM, Meredith KL, Shah NR, Kelley ST. Minimally Invasive Surgery for Esophageal Cancer. JNCCN. 6(9):879-84. Oct 2008.
- Farma JM, Ammori JB, Zager JS et al. Dermatofibrosarcoma protuberans: How wide should we resect?. Ann Surg Oncol. March 2010.
- Hernandez, JM, Farma JM, Coppola D, Hakam A, Fulp WJ, Chen DT, Siegel EM, Yeatman TJ, Shibata D. Expression of the anti-apoptotic protein surviving in colon cancer. Clinical Colorectal Cancer. April 2011.
- Nitzkorski JR, Farma JM, Watson JC, Zhu F, Siriurapu V, Matteoti RS, Sigurdson ER. Outcome and natural history of patients with stage IV colorectal cancer receiving chemotherapy without primary tumor resection. Ann Surg Oncol. August 2011.
- Arrangoiz R, Papavasiliou P, Farma J. Case Report and Literature Review: Metastatic Lobular Carcinoma of the Breast an Usual Presentation. International Journal of Surgery Case Reports. October 2011.
- Shanmugan S, Arrangoiz, R, Nitzkorski JR, Yu, JQ, Li T, Konski A, Farma JM. Sigurdson ER. Predicting pathologic response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer using FDG-PET/CT. Ann Surg Oncol. March 2012.
- Papavasiliou P, Arrangoiz, R, Farma JM. Utility of PET/CT in the staging and treatment of patients with Merkel cell carcinoma and melanoma. Journal of Nuclear Medicine & Radiation Therapy. Accepted for publication.
Book Chapters:
- Farma JM, Pingpank JF, Alexander HR. Isolated Hepatic Perfusion: Treating Unresectable Liver Metastases. Liver and Pancreatic Diseases Management (Advances in Experimental Medicine and Biology). Springer, New York, NY, April 2006.
- Farma JM, Tada H, Daly JM. Surgical management of metastatic liver disease. Surgical Oncology, Multidisciplinary Approach to Difficult Problems. Lippincott Williams & Wilkins, Philadelphia, September 2009.
- Santillan AA, Farma JM, Hagmaeir R, Cox CE, Riker AI. Hereditary Breast Cancer Syndromes. Inherited Cancer Syndromes-Current Clinical Management. November 2010.
- Rao PB, Farma JM. Palliative Gastrojejunostomy and the Impact on Nutrition in Cancer. Diet and Nutrition in Palliative Care. Taylor and Francis, CRC Press. May 2011.
- Papavasiliou, P, Zook M, Farma JM. Updates on Melanoma. Clinical Decision Support- Dermatology. Online publication.
Scientific Abstracts/Posters/Plenary Sessions:
- Goldberg M, Lampert C, Calorusso P, Coia L, Farma J, Frucht H, Goosenberg E, Beard M, Weiner LM. Survival following intensive preoperative combined modality therapy with paclitaxel, cisplatin, 5-flurouracil and radiation in respectable esophageal carcinoma: a phase 1 report. ASCO Annual Meeting, May 2002.
- Berger AC, Farma J, Wang H, Scott W, Goldberg M. Complete Response to Neoadjuvant Chemoradiotherapy in Esophageal Carcinoma is Associated with Significantly Improved Survival. ASCO GI Symposium, January 2004.
- Farma JM, Pingpank JF, Libutti SK, Chang R, Wood BJ, Neeman Z, Kam A, Seidel G, Beresneva, T, Alexander HR. Percutaneous Hepatic Perfusion (PHP) with Melphalan for Patients With Metastatic Melanoma (MM) to the Liver. ASCO GI Symposium, Hollywood, FL; January 2005.
- Farma JM, Puhlmann M, Weinreich DM, Alexander HR. Direct Evidence for Rapid and Selective Induction of Tumor Neovascular Permeability by Tumor Necrosis Factor (TNF) Using In Vivo Videomicroscopy (IVVM). Society of Surgical Oncology 58th Annual Cancer Symposium, Atlanta, GA; March 2005.
- Farma JM, Pingpank JF, Libutti SK, Chang R, Wood BJ, Neeman Z, Kam A, Seidel G, Beresneva, T, Alexander HR. Percutaneous Hepatic Perfusion (PHP) with Melphalan for Patients With Metastatic Melanoma (MM) to the Liver. Society of Surgical Oncology 58th Annual Cancer Symposium- Oral Presentation, Atlanta, GA; March 2005.
- Farma JM, Cox D, Soriano PA, Paciotti GF, Myer L, Tamarkin L, and Alexander HR. Targeting Effects of Colloidal Gold Bound Tumor Necrosis Factor (TNF) to Tumor Neovasculature Permeability Using In Vivo Video Microscopy (IVVM). 96th American Association for Cancer Research Annual Meeting, Anaheim, CA; April 2005.
- Farma JM, Hoffman JP. Non-Neoplastic Celiac Axis Occlusion in Patients Undergoing Pancreaticoduodenectomy(PD). 2006 Philadelphia Academy of Surgery Annual Resident Paper Competition, Philadelphia, PA; February 2006.
- Farma JM, Hoffman JP. Non-Neoplastic Celiac Axis Occlusion in Patients Undergoing Pancreaticoduodenectomy(PD). Midwest Surgical Association Annual Meeting-Oral Presentation, Mackinac Island, MI; August 2006.
- Farma JM, Melis M, Santillan AA, Walker J, Belinc D, Eikman EA, Malafa M. Positron Emission Tomography/ Computed Tomography Fusion Scans Enhances Preoperative Treatment Planning in Patients with Pancreatic Cancer. Society of Surgical Oncology 61st Annual Cancer Symposium- Oral Presentation, Chicago, IL; March 2008.
- Helm J, Centeno BA, Melis M, Farma JM, Malafa M. Tumor Differentiation and Extrapancreatic Invasion are More Predictive of Survival than the TNM System in Resected Pancreatic Cancer. Society of Surgical Oncology 61st Annual Cancer Symposium- Poster Presentation, Chicago, IL; March 2008.
- Farma JM, Melis M, Santillan AA, Walker J, Belinc D, Eikman EA, Malafa M. Positron Emission Tomography/ Computed Tomography Fusion Scans Enhances Preoperative Treatment Planning in Patients with Pancreatic Cancer. 2008 Moffitt Fellows Education Research Symposium- Poster Presentation, Tampa, FL; May 2008.
- Farma JM, Marzban SS, Puleo C, Bui MM, Messina JL, Sondak VK, Zager JS. Dermatofibrosarcoma protuberans (DFSP): How wide should we resect?. 2nd Annual World Meeting of Interdisciplinary Melanoma/Skin Cancer Centers- Oral Presentation, Clearwater, FL; November 2008.
- Farma JM, Coppola D, Chen D, Siegel EM, Hernandez JM, Yeatman TJ, Shibata D. Expression of the Anti-apoptotic Protein Survivin in Colon Cancer. ASCO GI Symposium, San Francisco, CA; January 2009.
- Farma JM, Marzban SS, Puleo C, Bui MM, Messina JL, Sondak VK, Zager JS. Dermatofibrosarcoma protuberans (DFSP): How wide should we resect? Society of Surgical Oncology 62nd Annual Cancer Symposium- Oral Presentation, Phoenix, AZ; March 2009.
- Farma JM, Coppola D, Chen D, Siegel EM, Hernandez JM, Yeatman TJ, Shibata D. Expression of the Anti-apoptotic Protein Survivin in Colon Cancer. Society of Surgical Oncology 62nd Annual Cancer Symposium- Poster Presentation. Phoenix, AZ; March 2009.
- Farma JM, Marzban SS, Rollison DE, Patel AI, Puleo CA, Cruse CW, Zager JS, Messina JL, Sondak VK. Uncovering chronic lymphocytic leukemia during sentinel lymph node biopsy for malignant melanoma. 6th International Symposium on Melanoma- Poster Presentation. New York, NY; March 2009.
- Farma JM, Marzban SS, Rollison DE, Patel AI, Puleo CA, Cruse CW, Zager JS, Messina JL, Sondak VK. Melanoma and chronic lymphocytic leukemia: evidence of an association. 7th World Congress on Melanoma- Oral Presentation. Vienna, Austria; May 2009.
- Farma JM, Coppola D, Chen D, Siegel EM, Hernandez JM, Yeatman TJ, Shibata D. Expression of the Anti-apoptotic Protein Survivin in Colon Cancer. 2009 Moffitt Fellows Education Research Symposium- Poster Presentation, Tampa, FL; May 2009.
- Farma JM, Marzban SS, Rollison DE, Patel AI, Puleo CA, Cruse CW, Zager JS, Messina JL, Sondak VK. Uncovering chronic lymphocytic leukemia during sentinel lymph node biopsy for malignant melanoma. 2009 Moffitt Fellows Education Research Symposium- Poster Presentation, Tampa, FL; May 2009.
- Farma JM, Marzban SS, Puleo C, Bui MM, Messina JL, Sondak VK, Zager JS. Dermatofibrosarcoma protuberans (DFSP): How wide should we resect? 2009 Moffitt Fellows Education Research Symposium- Poster Presentation, Tampa, FL; May 2009.
- Bui MM, Messina JL, Farma JM, Marzban SS, Sondak VK, Zager JS. Meticulous pathologic evaluation to ensure negative margins facilitates a low risk of local recurrence of dermatofibrosarcoma protuberans (DFSP). 15th Annual meeting of the connective tissue oncology society (CTOS)- Oral Presentation, Miami Beach, FL; November 2009.
- Nitzkorski JR, Farma JM, Matteoti R, Siripurapu V, Sigurdson ER. Outcome and natural history of patients with stage IV colorectal cancer treated with or without surgery after receiving chemotherapy. Philadelphia Academy of Surgery-Oral Presentation, Philadelphia, PA; May 2010.
- Siripurapu V, Shaw C, Anderson PR, Perlis CS, Topham NS, Wu H, vonMehren M, Lessin SR, Farma JM. Dermatofibrosarcoma protuberans with fibrosarcomatous transformation (DFSP-FS); Analysis of Outcomes. Connective Tissue Oncology Society 16th Annual Meeting- Poster Presentation, Paris, FR; November 2010.
- Stransky CA, Arrangoiz R, Farma JM, Berger AC, Papavasiliou P, Yu JQ, Sigurdson E, Mastrangelo M, Kairys J. Preoperative FDG-PET/CT (PET) is an important tool in the management of patients with thick (T4) melanoma. Philadelphia Academy of Surgery- Poster Presentation, Philadelphia, PA; January 2011.
- Shanmugan S, Arrangoiz, R, Nitzkorski JR, Yu, JQ, Li T, Konski A, Farma JM, Sigurdson ER. Predicting pathologic response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer using FDG-PET/CT. ASCO GI Symposium- Poster Presentation, San Francisco; January 2011.
- Nitzkorski JR, Willis AI, Farma JM, Cohen SJ, Zhu F, Nick DM, Sigurdson ER. Association of race and socioeconomic status and outcomes with patients with rectal cancer. ASCO GI Symposium- Poster Presentation, San Francisco, CA; January 2011.
- Shanmugan S, Arrangoiz, R, Nitzkorski JR, Yu, JQ, Li T, Konski A, Farma JM, Sigurdson ER. Predicting pathologic response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer using FDG-PET/CT. Society of Surgical Oncology 64thAnnual Cancer Symposium- Oral Presentation. San Antonio, TX; March 2011.
- Nitzkorski JR, Willis AI, Farma JM, Cohen SJ, Zhu F, Nick DM, Sigurdson ER. Association of race and socioeconomic status and outcomes with patients with rectal cancer. Society of Surgical Oncology 64thAnnual Cancer Symposium- Poster Presentation. San Antonio, TX; March 2011.
- Papavasiliou P, Arrangois R, Turaka A, Lango M, Yu JQ, Farma JM. Preoperative positron emission tomography/computed tomography changes management in patients with merkel cell carcinoma. Society of Surgical Oncology 64th Annual Cancer Symposium- Poster Presentation. San Antonio, TX; March 2011.
- Nitzkorski JR, Farma JM, Matteoti RS, Siriurapu V, Zhu F, Sigurdson ER. Outcome and natural history of patients with stage IV colorectal cancer receiving chemotherapy without primary tumor resection. Society of Surgical Oncology 64thAnnual Cancer Symposium- Oral Presentation. San Antonio, TX; March 2011.
- Arrangoiz R. Stransky CA, Papavasiliou P, Yu JQ, Li T, Kairys JC, Mastrangelo MJ, Sigurdson ER, Berger AC, Farma JM. Preoperative FDG-PET/CT (PET) is an important tool in the management of patients with thick (T4) melanoma. Society of Surgical Oncology 64thAnnual Cancer Symposium- Poster Presentation. San Antonio, TX; March 2011.
- Arrangoiz R, Papavasiliou P, Nitzkorski J, Yu JQ, Sigurdson E, Farma JM. Rectal Cancer Length by PET/CT Predicts Pathologic Complete Response. 97th American College of Surgeons Annual Clinical Congress -Poster Presentation. San Francisco, CA, October 2011.
- Turaka A, Murphy CT, Fang Z, Farma JM, Lango MN, Wu H, Engstrom P, Nicolaou N, Perlis C. Merkel cell carcinoma and sentinel lymph node evaluation: outcomes from a single institution. ASTRO 2011- Poster Presentation. Miami, FL; October 2011.
- Murphy CT, Turaka A, Fang Z, Farma JM, Lango MN, Wu H, Engstrom P, Nicolaou N, Perlis C. Adjuvant radiotherapy in merkel cell carcinoma: a 20-year experience at a single institution. ASTRO 2011- Poster Presentation. Miami, FL; October 2011.
- Pimiento JM, Boutrid H, Weber JM, Razzaque S, Farma JM, Kim RD, Hodul PJ, Shridhar R, Hoffe SE, Almhanna K, Chuong MD, Chen DT, Springett GM, Eikman E, Klapman , Jong P, Karl RC, Malafa MK. Low 18f-fluorodeoxyglucose uptake on positron emission tomography as a prognostic factor for stage I and II pancreatic cancer. ASCO GI 2012- Poster Presentation. San Francisco, CA; January 2012.
- Keller D, Thomay AA, Gaughan J, Wu H, Farma JM. Outcomes in Patients with Mucosal Melanomas. Resident Research Night: Philadelphia Academy of Surgery- Best Poster Presentation, Philadelphia, PA; February 2012.
- Arrangoiz R, Papavasiliou, P, Singla S, Siripurapu V, Watson JC, Hoffman JP, Farma JM. Partial Stomach-Partitioning Gastrojejunostomy (PSPG) and the success of this procedure in terms of palliation. 7th annual Academic Surgical Congress- Oral presentation, Las Vegas, NV; February 2012.
- Chen KT, Farma JM, Von Mehren M, Watson JC. Imatinib-resistant GIST metastases; predicting outcomes of surgical resection. 7th annual Academic Surgical Congress- Oral presentation, Las Vegas, NV; February 2012.
- Chen KT, Papavasiliou P, Zhu F, Perlis C, Wu H, Turaka A, Farma JM. Merkel Cell Carcinoma of Unknown Origin: A Better Prognosis? Society of Surgical Oncology 65TH Annual Cancer Symposium- Poster Presentation, Orlando, FL; March 2012.
- Keller D, Thomay AA, Gaughan J, Wu H, Farma JM. Outcomes in Patients with Mucosal Melanomas. Society of Surgical Oncology 65TH Annual Cancer Symposium- Poster Presentation, Orlando, FL; March 2012.
- Papavasiliou P, Chen KT, Arrangoiz, R, Murphy CT, Zhu F, Perlis C, Wu H, Turaka A, Farma JM. Optimal treatment approach for lymph node metastases in patients with Merkel cell carcinoma. Society of Surgical Oncology 65TH Annual Cancer Symposium- Poster Presentation, Orlando, FL; March 2012.
- Singla S, Papavasiliou P, Powers B, Gaughan J, von Mehren M, Watson JC, Farma JM. Challenges in treatment of angiosarcoma: A single institution experience. Society of Surgical Oncology 65TH Annual Cancer Symposium- Oral Presentation, Orlando, FL; March 2012.
- Pimiento JM, Boutrid H, Weber JM, Razzaque S, Farma JM, Kim RD, Hodul PJ, Shridhar R, Hoffe SE, Almhanna K, Chuong MD, Chen DT, Springett GM, Eikman E, Klapman , Jong P, Karl RC, Malafa MK. Low 18f-fluorodeoxyglucose uptake on positron emission tomography as a prognostic factor for stage I and II pancreatic cancer. Society of Surgical Oncology 65TH Annual Cancer Symposium- Poster Presentation, Orlando, FL; March 2012.
- Wai CJ, Meyer JE, Fang Z, Sigurdson E, Farma JM. Decreased use of chemoradiotherapy in patients with rectal cancer after treatment for prostate cancer. The American Society of Colon & Rectal Surgeons- Poster Presentation, San Antonio, TX; June 2012.
Invited Seminars and Grand Rounds:
- Surgery Branch, National Cancer Institute, Bethesda, MD.
In-Vivo Video Microscopy. May 2005. - Department of Surgery Grand Rounds, Temple University Hospital, Philadelphia, PA. Targeted Cancer Therapies: Are We There Yet?. May 2007.
- Multidisciplinary Fellow’s Conference Annual GI Symposium. H. Lee Moffitt Cancer Center, Tampa, FL. April 2008.
- Moderator, “Breakout session- Robotic Colorectal Surgery”, Advances in Robotic Surgery, Fox Chase Cancer Center, Philadephia, PA. November 2009.
- Invited Guest, Hunterdon Medical Center Tumor Board, November 2009.
- Invited Speaker, Philadelphia Dermatological Society, Philadelphia, PA. December 2009.
- Invited Speaker, CME Conference: Updates on the Current Treatment of Melanoma, South Jersey Healthcare, Vineland, NJ. January 2010.
- Invited Guest, Hunterdon Medical Center Tumor Board, December 2010.
- Invited Speaker, Philadelphia Dermatological Society, Philadelphia, PA. February 2011.
- Co-chair colorectal breakout session. Fox Chase Cancer Center Annual GI retreat. February 2011.
- Invited Speaker, “Minimally Invasive Surgical Oncology”, Reduced Port Surgery First International Symposium, Philadelphia, PA. June 2011.
- Moderator, SSO Surgical Oncology National Videoconference Series, July 6, 2011.
- Invited Speaker, “Surgical Treatment of Melanoma”, Oncology Noon Conference Series, Fox Chase Cancer Center, Philadelphia, PA. August 2011.
- Invited Speaker, “Neoadjuvant Chemoradiation for Rectal Cancer”, Roger Smith, MD Memorial Lecture, Pottstown Memorial Hospital, Pottstown, PA. October, 2011.