Clinical Expertise:
Ovarian Cancer, Endometrial Cancer, Uterine Sarcoma,Vulvar Cancer and Cervical Cancer; Gestational Trophoblastic Disease; Laparoscopic Surgery; Complex Gynecologic Surgery
Certifications:
American Board of Obstetrics and Gynecology
I joined Fox Chase Cancer Center family in 2009 because it is the region's only hospital devoted entirely to cancer treatment and dedicated to cutting-edge research. I am a gynecological oncologist who specializes in surgical treatment of gynecologic cancers and complex benign gynecologic conditions. In addition to performing traditional open surgical procedures for staging and debulking, I have special interests in minimally invasive laparoscopic surgeries.
Fox Chase Cancer Center is committed to improving cancer treatments and the quality of life for patients with gynecologic cancer. Team approach to cancer care is accomplished through a mutidisciplinary team of doctors who work together to guide each patient through diagnosis, treatment, and recovery. Using this approach, the treatment plans reflect the combined expertise of many doctors — gynecologic oncologist, medical oncologists, radiologists, radiation oncologists, and pathologists. This unified approach also ensures that patients who need several different therapies to treat their cancer will receive the ideal care and provides comprehensive and coordinated care. In addition, through leading edge research, clinicians and scientists collaborate to discover more effective therapies for gynecologic cancers. Translational research brings new knowledge and treatments from the laboratory to the patient’s bedside as quickly as possible.
I was one of the first Fox Chase surgical oncology members to provide comprehensive care at both Fox Chase Cancer Center and Virtua in South Jersey through its Partners Program, expanding the Center’s efforts in bringing clinical trials to South Jersey and offer more treatment options in gynecological oncology to the community.
Using my training in Clinical Epidemiology, I hope to develop novel and innovative clinical trials in gynecologic oncology and collaborate with Fox Chase scientists in advancement of translational research. I hope to continue bringing the fight for women cancers even more to the forefront of public awareness.
Medical Education
Masters of Science in Clinical Epidemiology., University of Pennsylvania School of Medicine, Philadelphia, PA, 2009;
MD, Upstate Medical University, SUNY College of Medicine, 2000
Residencies
Resident in Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2004
Fellowships
Gynecologic Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2007
Research Interests
Clinical trials in gynecologic cancer;
Targeted therapies in gynecologic cancer;
Biomarkers to predict responses to targeted therapies
Publications
Lectures by Invitation (Last 5 years):
Aug, 2007 "New Advances in Ovarian Cancer Therapy and Research"
Moms on the Move, Channel NBC10
Sep, 2007 "Challenges and Opportunities in Ovarian Cancer Therapy"
Teal Talk over Tea, National Ovarian Cancer Coalition
Fairmount Water Works, Philadelphia, PA
Mar, 2008 Guest Lecturer, Annual Resident Research Presentation
Cooper University Hospital, UMDNJ
Apr, 2008 Eighth Annual Focus on Gynecologic Cancers Conference, Hilton Hotel, Philadelphia, PA
Research Publications, peer reviewed (print or other media):
- Maguire H, Berd D, Lattime E, McCue P, Kim S, Chapman P, Mastrangelo M: Phase I Study of R24 in Patients with Metastatic Melanoma Including Evaluation of Immunological Parameters. Cancer Biother & Radiopharm 13(1):13-23, 1998.
2. Slovin SF, Ragupathi G, Adluri S, Ungers G, Terry K, Kim S, Livingston PO, Scher HI: Carbohydrate Vaccines in Cancer: Immunogenicity of a Fully Synthetic Globo H Hexasaccharide Conjugate in Man. Proc Natl Acad Sci 96:5710-5715, 1999.
3. Kim S, Srinivas S, Rubin S, Freedman L, Gray H: Delayed Hemorrhage after Cervical Conization Unmasking Severe Factor XI Deficiency. Obstet Gynecol 104(5):1189-1192, 2004.
4. Buckanovich RJ, Facciabene A, Kim S, Benecia F, Sasaroli D, Balint K, Katsaros D, O'Brien-Jenkins A, Gimotty PA, Coukos G: Endothelin (B) Receptor Mediates the Endothelial Barrier to T-Cell Homing to Tumors, and its Neutralization Enables Tumor Immune Therapy. Nat Med 14(1):28-36, 2008.
5. Chu CS, Kim S, June CH, Coukos G: Immunotherapy Opportunities in Ovarian Cancer. Expert Rev Anticancer Ther 8(2):1-5, 2008.
6. Yang N, Huang J, Greshock J, Liang S, Barchetti A, Hasegawa K, Kim S, Giannakakis A, Li S, O'Brien-Jenkins A, Katsaros D, Butzow R, Coukos G, Zhang L: Transcriptional Regulation of PIK3CA Oncogene by NF-xB in Ovarian Cancer Microenvironment. PLoS One 12(3):e1758, 2008.
7. Gimotty P, Zhang L, Alagkiozidis I, Kim S, Cadungog M, Adams S, Chu CS, Katsaros D, Coukos G: Immune Porgnostic Factors in Ovarian Cancer: Lessons from Translational Research. Dis Markers, 23(5-6):445-52.
8. Kim S, Liao J, Chu CS, Coukos G: Tumor microenvironment: Biomarker for use of immunoassessment cancer vaccines? under review.
9. Kim S, Morgan M, Coukos G, Rubin S, Chu C: Analysis of Survival Outcomes of Stage I Clear Cell Carcinoma of the Ovary, under review.
Research Publications
- Kim S, Hageman A, DeMichele A. Immuno-Modulatory Gene Polymorphisms and Outcome in Breast and Ovarian Cancers, Immunol Invest, in press.
Abstracts (Last 3 years):
- 1. Buckanovich R, Kim S, Benecia F, Sasaroli D, Gimotty P, Coukos G: Antagonism of endothelin receptor B increases intratumoral T-cell trafficking and effectively enhances antitumor vaccine therapy of ovarian cancer. Poster presentation at the Society of Gynecologic Oncologists 37th Annual Meeting, March, 2006.
- Kim S, Buckanovich R, Katsaros D, Gimotty P, Coukos G: Endothelin receptor B as a biomarker of suboptimal cytoreduction and poor clinical outcome in epithelial ovarian carcinoma. Poster presentation at the Society of Gynecologic Oncologists 37th Annual Meeting, March, 2006.
- Kim S, Lee K, Chu C: HER2/neu expression in primary and recurrent epithelial ovarian cancer. Poster presentation at the Western Association of Gynecologic Oncologists 35th Annual Meeting, May, 2006.
- Kim S, Gleason J, Buckanovich R, Sasaroli D, Chu C, Katsaros D, Gimotty P, Dumoff K, Coukos G: Neuropillin-2 as biomarker of poor clinical outcomes in epithelial ovarian cancers. Poster presentation at the Society of Gynecologic Oncologists 39th Annual Meeting, March, 2008.
- Kim S, Lee K, Gleason J, Adams S, Cadungog M, Chu C, Katsaros D, Gimotty P, Dumoff K, Coukos G: Presence of intratumoral T cells in recurrent ovarian cancer predicts favorable clinical outcomes. Poster presentation at the Society of Gynecologic Oncologists 39th Annual Meeting, March, 2008.
- Kim S, McCann G, Chu CS. Adjuvant sandwich regimen of chemotherapy and radiation for advanced endometrial cancer. Oral presentation at the Mid-Atlantic Gynecologic Oncology Society 23rd Annual Meeting, September 2008.
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