Research at Fox Chase »Research Facilities »Biotechnology

Tony Yeung 215-728-2488 Anthony.Yeung@fccc.edu Reimann Building Room R404 Director Glenn Miller 215-728-2858 oligo@fccc.edu Reimann Building Room R150 Facility Manager Yibai Chen 215-728-3410 Yibai.Chen@fccc.edu Reimann Building Room R157 Research Associate Xin-Ming Li, Ph.D. 215-214-1456 Xin-Ming.Li@fccc.edu Reimann Building Room R444 Research Associate Philip Do, Ph.D. 215-728-2858 oligo@fccc.edu Reimann Building Room R150 Scientific Technician Jing Cui.Zhou 215-728-2858 oligo@fccc.edu Reimann Building Room R404 Scientific Technician

Reimann Building Fax: 215-728-3647 Oligo Fax Orders: 215-728-4331

Function

The Biochemistry and Biotechnology Facility (BBF) makes available to Fox Chase investigators five state-of-the-art services that are connected to each other in research applications. Through BBF, translational research projects gain instant access to equipment, manpower, and expertise in cutting edge technologies and new investigators can quickly get up to speed.

• DNA Synthesis provides uniformly high quality DNA, RNA, and modified oligonucleotides, and the assembly of designer genes. Because of quality control, oligonucleotides from BBF have never been a variable in the users' experiments.
• The full-service Real-time PCR facility provides highly accurate quantitation of nucleic acid levels in samples.
• The BBF provides access to modern Mass Spectrometry. Services include high sensitivity protein analysis and identification, partial peptide sequencing, characterization of post-translational modifications, DNA analysis, drug chemistry, and enzyme characterization.
• Proteomic services by BBF provide expertise in 2D gel resolution of proteins, image acquisition and automated analysis. Interesting protein spots selected are used for protein identification with the assistance of robotics and state of the art mass spectrometers. Proteomic projects are coordinated with the HPLC service
• The HPLC service provides expert protein purification. Proteins available in microgram quantities are purified or analyzed using the FPLC/SMART chromatography systems.