Research at Fox Chase »Research Facilities »Computing and Information

Eric Ross, PhD Assistant Professor and Senior Director of Academic Informatics Facility Director Sam Litwin, PhD Associate Professor Karthik Devarajan, PhD Assistant Professor Brian Egleston, PhD Assistant Professor Fang Zhu, PhD Instructor Tianyu Li, MS Research Statistician Suraj Peri, PhD Senior Bioinformatics Specialist Karen J. Ruth, MS Research Biostatistician Michael Slifker, MS Senior Programmer Analyst Yan Zhou, MSE PhD Bioinformatics Specialist Arlene Capriotti Administrative Assistant

Reimann Building, Room R383 215-728-4330 215-728-2891 Arlene.Capriotti@fccc.edu

Function:

The Biostatistics and Bioinformatics Facility is a shared institutional resource for statistical and bioinformatics consulting and related methodological research. The specific aims of the facility are to:

• provide statistical design of experiments and studies
• provide statistical analysis for Center projects and assist in the interpretation and presentation of results
• provide functional genomics and DNA sequence analysis
• provide statistical and bioinformatics components of grant applications and manuscripts
• review the study design and statistical quality of all protocols involving human subjects as members of the Research Review Committee
• monitor and report clinical data in collaboration with the Protocol Office
• devise new quantitative methods when needed for specific application to problems arising in Center investigations

Electronic Request for Service
The preferred method to obtain biostatistics and bioinformatics support is to use our short electronic request form at http://research.fccc.edu/facilities/biostat (internal access only).

Description:

Available statistical software includes standard packages such as SAS (version 9), R, Minitab, StatXact, S-PLUS, STATA, and AMOS; sample size and power computation applications such as Pass 2000, Solo Power Analysis, and custom written applications; tools for methodological research such as Mathematica, Matlab; and a number of publicly available tools for data analysis (e.g., BRB from the NCI, Bioconductor).

The facility also maintains and routinely updates copies of a variety of molecular databases and numerous scientific software licenses for general use, including the GCG Sequence Analysis Software Suite, SeqWeb, MacVector, and Sequencher. The facility has also deployed and customized BioDiscovery's GeneDirector microarray database system. Custom software development is available when existing software does not meet investigator needs.