Research at Fox Chase »Research Facilities »Genetic Research

Joseph R Testa, PhD Director

Prevention Pavilion, Room 3001A 215-728-2610 Joseph.Testa@fccc.edu

Recently, Fox Chase Cancer Center merged five core service laboratories: Research Cytogenetics & Genomics, DNA Microarray, Genotyping & Biomarker, Real-time PCR, and Laser Capture Microdissection into a single Genomics Facility.

Cytogenetics and Chromosome Microarray Analysis

Cytogenetics and Chromosome Microarray Analysis provides services to assist Fox Chase investigators in research projects that require karyotyping, molecular cytogenetic analysis, and DNA copy number/aCGH analysis at a reasonable cost. More

Expression Microarray

Expression microarray provides full hybridization services using two main microarray platforms: Agilent oligo arrays and Affymetrix Genechip. Both systems are capable of performing global gene expression profiling for a variety of species, as well as miRNA expression analysis. Other services include RNA isolation, array experiment design, data analysis and management, as well as custom array printing. More

Genotyping and Real-Time PCR

Genotyping and Real-Time PCR performs PCR-based services including genotyping of transgenic and knock-out mice, mutations and epigenetic alterations analyses and quantification of nucleic acids. New assays are developed based on investigators' needs. More

Laser Capture Microdissection

Laser Capture Microdissection provides the researcher with a means to isolate a pure population of cells from heterogeneous tissue specimens. These "captured" cells can then be used in a wide range of downstream assays such as gene expression analysis, loss of heterozygosity studies, or proteomic assays, etc. More