This page is still under construction
 
 

Applications of Dual Bait system

 

Library screening:

One-step screening library of Activation Domain-fused prey proteins...
... or peptides to identify specific interaction

 

 

Mutational analysis or drug screening:

Starting point in mutational analysis or drug screening using Dual Bait: prey protein, expressed as fusion to Activation Domain, interacts with both baits
Mutated prey specifically interacts with only one of the baits
Small molecule or peptide specifically interacts with either bait or prey (as shown), blocking one of the interactions