Table of false positives

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See a list of articles using any kind of two-hybrid system (published till October 1995)

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bait type actual bait trash
* if truncated
G prot beta subunit *
G prot alpha subunit 16S rRNA; ribosom. S12; mitochondrial protein
adaptor HEF1* ferritin; keratin; PAS; hsp90; vimentin; ATP-synth.; novel collagen-like protein
adaptor . 4 different tfs, RNA helicase, transferase, nucleoproteins
ank-rep * mitochondrial, ribosomal proteins
ank-rep Krit1* ribosomal, mitochondrial, DHFR, NADH-reductase
chromos.p HP1 oof,*
dbp * SEC7, *
dbp DNA topo-isomerase I human PCNA
dbp DNA-pol alpha cytochrome oxidase, chorian prot.
GTPase dynamin* extensin
helicase RNA helicase cytoskeletal prot. Z17335
hsp aB crystallin proteasome;*
kinesin-related * Topoisomerase I, glycosyl hydrolase
meiosis SCP1* *
meiosis SCP3 mitochondrial; transmemb.prot.
multisynt. comp ATPase, P63, MSS1,SP-40
pk Fes* ?hsp90, ?proteasome
pk * cytchrome C oxidase subunit Vb.
pk . hsp70?
pk Mst1 PQ rich, NKEF/PAG, ATPase, LIM-containing, CRP homolog, Zn-finger; SLAP2 homolog, *
pk FYN* collagen precursor; *
pk Fen rubisco
pk Pto *?
pk Pti1 *?
pk Arg* no
pp * *
prion . prolyl 4-hydroxylase alpha subunit; *
protease 2A *
rbp . PCNA; *
rec/ DNA rep. * annexin II
recep p75* hsp60, phosphoriboprotein
recep . 5 different tfs
recep . mitochondrial cytochrome oxidase
recep TNF-recep* phosphoglycerate mut., macroph. migr. inhib.f.
recep TGF beta II *
recep IGF-I *?
recep trkB *
recep * ribos.L9,L23a,S6; glycerald. dehyd.,dbp, NADH dehyd.
recep . cyclin B
recep * *
repl? . none
RNApol PAP PIP1
RNApolII hsRPB7 ribos.L20,
RNA-pol RNAdep RNA-pol UBCEPs (ubiqutin-carboxylext.)
ribosomal L7 oof; *?
spl ORF3 *
spl . *
spl * ribosomal L21;?*
structural major vault protein none
tf Fushi tararu* 16S rRNA
tf . cytchrome C oxidase; ubiquitin; conflin; *
tf * ferritin-like?, *
tf E2-2* oof
tf glucocorticoid receptor* none
tf SRF 40S ribosomal, mucin, gastrin bind., human elong. factor 1
tf Asx ribosomal L34, spermidine synth.
tf thyroid hormone recep. alpha 1 mitoch hsp, ribosomal, tRNA synth., farnesyltransferase
tf CIITA *
tf . empty vector
tr . *
tRNA synth * ubiquitin/ribosome S27a, 26S protease, hsp90
Ubiquitin-conjugating . ribosomal
Ubiquitin-conjuggating bendless *
viral small antigen syntropin, new Zn finger pr.
viral non-structural NS5A *
o * endoplasmin, creatine kinase
o MO15/CDK7 hsp90, *
o Cln3 2 pk; *
o Vir2 leu2 homolog
o CNP hsp70, hsp86, reverse collagen
o Frzb actin-pseudogene, *
o . hsp; ferritin; tRNA synth.; CG-binding prot.; fibronectin binding prot.
o X-protein* hsp, protein disulfite isomerase,
o * *
o . none
o . vimentin
o hook mitoch.16S RNA, hsp70, tRNA synths, inorg. pyrophosphatase, yolk protein...
o E3 14.7 kD alpha enolase
o Superox. Dism. *
o L1 52/55 K protein *
o calmodulin yeast ADH, cytoch. C oxidase, mitoch. ribosomal
o APP* ?
o * hsp90
o Oskar proteasome subunit
o NF2* ubiquitin
o P16 mitochondrial
o cappuccino ribosomal protein
o ArgBP1* ferritin, hsp
o ArgBP2* hsp, ferritin, NST-1, LPE7W
o torso-like *
o bag-of-marbles* inorganic pyrophosph.
o p80 coilin hsp90, ssra, *
o p-glycoprot* ZNFI43, EWS
o . proteasome subunit
5 diff. transmemb cyt. domains ribosomal,*

Common abbreviations:

tf, transcription fastor(s);

spl, splicing involved;

tr, transcription involved;

ank-rep, containing ankiryn repeats;

synth, synthase;

recep, receptor;

ribos, ribosomal;

mitoch, mitochondrial;

dbp, DNA binding protein;

rbp, RNA binding protein;

oof, out of frame

o, others

* in the "trash" column: not specified or not investigated

? in the trash column: not sure if trash

? in the bait column: not sure of bait function

If no actual bait name is given: not specified by author or confidential at this stage.

Back to the introduction page

See a list of articles using any kind of two-hybrid system (published till October 1995)

Go to the Table summarizing some of the two-hybrid system usage