Faculty Summaries
Tahseen I Al-Saleem, MD
Tahseen I Al-Saleem, MD
Research Interests

Cancer is due to cells that run out of control. My laboratory aims to study the body’s immune response to cancer. Understanding why the response to cancer weakens the body will allow us to strengthen the ability to control the disease.


-Contribute to the development of animal models for lymphoma. 
-Investigation and description of new or unusual hemopoietic malignancies.

Description of research projects
Selected Publications
  1. Reyes VE Jr, Al-Saleem T, Robu VG, Smith MR. Extranodal NK/T-cell lymphoma nasal type: Efficacy of pegaspargase. Report of two patients from United States and review of literature. Leuk Res. 2010 Jan;34(1):e50-4. Epub 2009 Sep 27. PubMed
  2. Pollack A, Bae K, Khor LY, Al-Saleem T, Hammond ME, Venkatesan V, Byhardt RW, Asbell SO, Shipley WU, Sandler HM. The importance of protein kinase A in prostate cancer: relationship to patient outcome in Radiation Therapy Oncology Group trial 92002. Clin Cancer Res. 2009 Sep 1;15(17):5478-84. Epub 2009 Aug 25. PubMed
  3. Kadariya Y, Yin B, Tang B, Shinton SA, Quinlivan EP, Hua X, Klein-Szanto A, Al-Saleem TI, Bassing CH, Hardy RR, Kruger WD. Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma. Cancer Res. 2009 Jul 15;69(14):5961-9. Epub 2009 Jun 30. PubMed
  4. Khor LY, Bae K, Paulus R, Al-Saleem T, Hammond ME, Grignon DJ, Che M, Venkatesan V, Byhardt RW, Rotman M, Hanks GE, Sandler HM, Pollack A. MDM2 and Ki-67 predict for distant metastasis and mortality in men treated with radiotherapy and androgen deprivation for prostate cancer; RTOG 92-02. J Clin Oncol. 2009 Jul 1;27(19):3177-84. Epub 2009 May 26. PubMed
  5. Gitelson E, Al-Saleem T, Smith MR. Lymphomatoid granulomatosis; challenges in diagnosis and treatment. Clin Adv Hematol Oncol. 2009 Jan;7(1):68-70. PubMed
  6. Shafer D, Wu H, Al-Saleem T, Reddy K, Borghaei H, Lessin S, Smith M. Cutaneous precursor B-Cell lymphoblastic lymphoma in2 adult patients: clinicopathologic and molecular cytogenetic studies with a review of the literature. Arch Dermatol. 2008 Sep;144(9):1155-62. PubMed
  7. Jambusaria A, Shafer D, Wu H, Al-Saleem T, Perlis C. Cutaneous plasmablastic lymphoma. J Am Acad Dermatol. 2008 Apr;58(4):676-8. PubMed
  8. Rothman J, Crispen PL, Wong YN, Al-Saleem T, Fox E, Uzzo RG. Pathologic concordance of sporadic synchronous bilateral renal masses. Urology. 2008 Jul;72(1):138-42. Epub 2008 Mar 12. PubMed
  9. Potapova A, Hoffman AM, Godwin AK, Al-Saleem T, Cairns P. Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer. Cancer Res. 2008 Feb 15;68(4):998-1002. PubMed
  10. D'Ambrosio DJ, Hanlon AL, Al-Saleem T, Feigenberg SJ, Horwitz EM, Uzzo RG, Pollack A, Buyyounouski MK. The proportion of prostate biopsy tissue with Gleason pattern 4 or 5 predicts for biochemical and clinical outcome after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys. 2007 Mar 15;67(4):1082-7. Epub 2007 Jan 22. PubMed
  11. Narra K, Borghaei H, Al-Saleem T, Höglund M, Smith MR. Pure red cell aplasia in B-cell lymphoproliferative disorder treated with rituximab: report of two cases and review of the literature. Leuk Res. 2006 Jan;30(1):109-14. Epub 2005 Jul 25. PubMed
  12. Gitelson E, Al-Saleem T, Millenson M, Lessin S, Smith MR. Cutaneous B-cell lymphoma responds to rituximab: a report of five cases and a review of the literature. Leuk Lymphoma. 2006 Sep;47(9):1902-7. PubMed
  13. Al-Saleem T, Balsara BR, Liu Z, Feder M, Testa JR, Wu H, Greenberg RE. Renal oncocytoma with loss of chromosomes Y and 1 evolving to papillary carcinoma in connection with gain of chromosome 7. Coincidence or progression? Cancer Genet Cytogenet. 2005 Nov;163(1):81-5. PubMed
  14. Al-Saleem T, Al-Mondhiry H. Immunoproliferative small intestinal disease (PSID): a model for mature B-cell neoplasms. Blood. 2005 Mar 15;105(6):2274-80. Epub 2004 Nov 12. PubMed
  15. Dulaimi E, Ibanez de Caceres I, Uzzo RG, Al-Saleem T, Greenberg RE, Polascik TJ, Babb JS, Grizzle WE, Cairns P. Promoter hypermethylation profile of kidney cancer. Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):3972-9. PubMed
All publications