Mary B Daly, MD, PhD

Chair, Department of Clinical Genetics
Timothy R. Talbot Jr. Endowed Chair in Cancer Research

Mary.Daly@fccc.edu
Phone: 215-728-2791
Fax: 215-728-4061

Recent Publications

2005

Bruner, D.W., Linton, S., Konski, A., Uzzo,R.B., Greenberg, R.E., Pollack, A., Gordon, R., Cescon, T.P., Daly, M., Young, W., Goplerud, J., Tofani, S.H., Engstrom, P. "Successful Strategies for African American Recruitment to Prostate Cancer Research," International Journal of Cancer Prevention 1(4):295-306, 2005.

Larson, G.P., Ding, Y., Cheng, L. S-C., Lundberg, C., Gagalang, V., Rivas, G., Geller, L., Weitzel, J., MacDonald, D., Archambeau, J., Slater J., Neuberg, D., Daly, M.B., Angel, I., Benson III, A.B., Smith, K., Kirkwood, J.M., O'Dwyer, P.J., Raskay, B., Sutphen, R., Drew, R., Stewart, J.A., Werndli, J., Johnson, D., Ruckdeschel, J.C., Elston, R.C., Krontiris, T.G. "Genetic Linkage of Prostate Cancer Risk to the Chromosome 3 Region Bearing FHIT," Cancer Research 65(3):805-814, 2005.

2004

Dulaimi, E., Hillinck, J., de Caceres II, Al-Saleem, T., Cairns, P. Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients. Clin. Cancer Res. 10:6189-6193, 2004.

Daly, M.B. "Tailoring Breast Cancer Treatment to Genetic Status: The Challenges Ahead," J. Clin. Oncol. 22:1-2, 2004.

Daly, M.B., Ozols, R.F. "Symptoms of Ovarian Cancer - Where to Set the Bar?" JAMA 291(22):2755-2756, 2004.

Jernstrom, H., Lubinski, J., Lynch, H.T., Ghadirian, P., Neuhausen, S., Isaacs, C., Weber, B.L., Horsman, D., Rosen, B., Foulkes, W.D., Friedman, E., Gershoni-Baruch, R., Ainsworth, P., Daly, M., Garber, J., Olsson, H., Sun, P., Narod, S.A. "Breast-feeding and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers," J Natl Cancer Inst 96:1094-1098, 2004.

John, E.M., Hopper, J.L., Beck, J.C., Knight, J.A., Neuhausen, S.L., Senie, R.T., Ziogas, A., Andrulis, I.L., Anton-Culver, H., Boyd, N., Buys, S.S., Daly, M.B., O'Malley, F.P., Santella, R.M., Southey, M.C., Venne, V.L., Venter, D.J., West, D.W., Whittemore, A.S., Seminara, D. for the Breast Cancer Family Registry. "The Breast Cancer Family Registry: An Infrastructure for Cooperative Multinational, Interdisciplinary and Translational Studies of the Genetic Epidemiology of Breast Cancer," Breast Cancer Research 6:R375-R389, 2004.

Ozols, R.F., Bookman, M.A., Connolly, D.C., Daly, M.B., Godwin, A.K., Schilder, R.J., Xu, X., Hamilton, T.C. "Focus on Epithelial Ovarian Cancer," Cancer Cell 5:19-24, 2004.

Rebbeck, T.R., Friebel, T., Lynch, H.T., Neuhausen, S.L., van't Veer, L., Garber, J.E., Evans, G.R., Narod, S.A., Isaacs, C., Matloff, E., Daly, M.B., Olopade, O.I., Weber, B.L. "Bilateral Prophylactic Mastectomy Reduces Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group," J. Clin. Oncol. 22(6):1055-1062, 2004.

Sein, E., Mazzoni, S., Masny, A., Stearman, B. Process evaluation of community-based cancer risk assessment programs. Oncol. Issues 19:32-36, 2004.

Smith, E.R., Daly, M.B., Xu, X.X. "A Mechanism for Cox-2 Inhibitor Anti-inflammatory Activity in Chemoprevention of Epithelial Cancers," Cancer Epidemiology, Biomarkers & Prevention," 13(1):144-5, 2004.

Whittemore, A.S., Balise, R.R., Pharoah, P.D., Dicioccio, R.A., Oakley-Girvan, I., Ramus, S.J., Daly, M., Usinowicz, M.B., Garlinghouse-Jones, K., Ponder, B.A., Buys, S., Senie, R., Andrulis, I., John, E., Hopper, J.L., Piver, M.S. "Oral Contraceptive Use and Ovarian Cancer Risk Among Carriers of BRCA1 or BRCA2 Mutations," Br J Cancer 91(11):1911-1915, 2004.

2003

Fang, C.Y., Schultz, D.C., Guo, S., Vanderveer, L., Dangel, J., Bove, B., Daly, M., Godwin, A.K. Psychosocial correlates of intention to undergo prophylactic oophorectomy among women with a family history of ovarian cancer. Prev. Med. 37:424-431, 2003.

Ozols, R.F., Daly, M.B., Klein-Szanto, A., Hamilton, T.C., Bast, R.C., Jr., Brewer, M.A. Specific keynote: Chemoprevention of ovarian cancer: the journey begins. Gynecol. Oncol. 88:S59-66; discussion S67-70, 2003.

Prowse, A., Schultz, D.C., Guo, S., Vanderveer, L., Dangel, J., Bove, B., Daly, M., Godwin, A.K. Identification of a novel splice acceptor site mutation in p16INK4A/p14ARF within a breast cancer, melanoma, neurofibroma-prone kindred. J. Med. Genet. 40:e102, 2003.

Roland, I.H., Yang, W.-L., Yang, D.-H., Daly, M.B., Ozols, R.F., Hamilton, T.C., Lynch, H.T., Godwin, A.K., Xu, X.-X. Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies. Cancer 98:2607-2623, 2003.

Wagner Costalas J., Itzen, M., Malick, J., Babb, J.S., Bove, B., Godwin, A.K., Daly, M.B. Communication of BRCA1 and BRCA2 results to at-risk relatives: A cancer risk assessment program's experience. Am. J. Med. Genet. 119C:11-18, 2003.

2002

Andrulis, I.L., Anton-Culver, H., Beck, J., Bove, B., Boyd, J., Buys, S., Godwin, A.K., Hopper, J.L., Li, F., Neuhausen, S.L., Ozcelik, H., Peel, D., Santella, R.M., Southey, M.C., van Orsouw, N.J., Venter, D.J., Vijg, J., Whittemore, A.S.; Cooperative Family Registry for Breast Cancer Studies. Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations. Hum. Mutat. 20(1):65-73, 2002.

Calzone, K.A., Jenkins, J., Masny, A. Core competencies in cancer genetics for advanced practice oncology nurses. Oncol. Nurs. Forum 29(9):1327-1333, 2002.

Daly, M.B. Epidemiology and clinical risk factors. In Breast Cancer. A Guide to Detection and Multidisciplinary Therapy, edited by M.H. Torosian. Humana Press, Totowa, pp. 3-18, 2002.

Daly, M.B., Ozols, R.F. The search for predictive patterns in ovarian cancer: proteomics meets bioinformatics. Cancer Cell 1(2):111-112, 2002.

Fang, C.Y., Miller, S.M., Daly, M.B., Hurley, K. The influence of attentional style and risk perceptions on intentions to undergo prophylactic oophorectomy among first-degree relatives. Psychology and Health 17(3):365-376, 2002.

Narod, S.A., Dube, M-P., Klijn, J., Lubinski, J., Lynch, H.T., Ghadirian, P., Provencher, D., Heimdal, K., Moller, P., Robson, M., Offit, K., Isaacs, C., Weber, B., Friedman, E., Gershoni-Baruch, R., Rennert, G., Pasini, B., Wagner, T., Daly, M., Garber, J.E., Neuhausen, S.L., Ainsworth, P., Olsson, H., Evans, G., Osborne, M., Couch, F., Foulkes, W.D., Warner, E., Kim-Sing, C., Olopade, O., Tung, N., Saal, H.M., Weitzel, J., Merajver, S., Gauthier-Villars, M., Jernstrom, H., Sun, P., Brunet, J-S. Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. J. Natl. Cancer Inst. 94:1773-1779, 2002.

Rebbeck, T.R., Lynch, H.T., Neuhausen, S.L., Narod, S.A., van't Veer, L., Garber, J.E., Evans, G., Isaacs, C., Daly, M.B., Matloff, E., Olopade, O.I., Weber, B.L. Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. N. Engl. J. Med. 346:1616-1622, 2002.

Thompson, D., Szabo, C.I., Mangion, J., Oldenburg, R.A., Odefrey, F., Seal, S., Barfott, R., Droeze-Jansema, K., Teare, D., Reahman, N., Renard, H., Mann, G., Hopper, J.?L., Buys, S.S., Andrulis, I.L., Senie, R., Daly, M.B., West, D., Ostrander, E.A., Offit, K., Peretz, T., Osorio, A., Benitez, J., Nathanson, K.L., Sinilnikova, O.M., Olah, E., Bignon, Y.J., Ruiz, P., Badzioch, M.D., Vasen, H.F., Futreal, A.P., Phelan, C.M., Narod, S.A., Lynch, H.T., Ponder, B.A., Eeles, R.A., Meijers-Heijboer, H., Stoppa-Lynonnet, D., Couch, F.J., Eccles, D.M., Evans, D.G., Chang-Claude, J., Lenoir, G., Weber, B.L., Devilee, P., Easton, D.F., Godgar, D.E., Stratton, M.R., KconFab Consortium. Evaluation of linkage of breast cancer to the putative BRCA2 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium. Proc. Natl. Acad. Sci. USA 99(2):827-831, 2002.

2001

Beck, J.C., Beiswanger, C.M., John, E.M., Satariano, E., West, D. Successful transformation of cryopreserved lymphocytes: a resource for epidemiological studies. Cancer Epidemiol. Biomark. Prev. 10:551-554, 2001.

Narod, S.A., Sun, P., Ghadirian, P., Lynch, H., Isaacs, C., Garber, J., Weber, B., Karlan, B., Fishman, D., Rosen, B., Tung, N., Neuhausen, S.L., and the Hereditary Ovarian Cancer Clinical Study Group. Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: A case control study. Lancet 357:1467-70, 2001.

Daly, M.B., Barsevick, A., Miller, S.M., Buckman, R., Costalas, J., Montgomery, S., Bingler, R. Communicating genetic test results to the family: a six-step, skills-building strategy. Fam. Community Health 24(3):13-26, 2001.

Rebbeck, T.R., Wang, Y., Kantoff, P.W., Krithivas, K., Neuhausen, S.L., Godwin, A.K., Daly, M.B., Narod, S.A., Brunet, J-S., Vesprini, D., Garber, J.E., Lynch, H.T., Weber, B.L., Brown, M. Modification of BRCA1- and BRCA2- associated breast cancer risk by AIB1 genotype and reproductive history. Cancer Res. 61:5420-5424, 2001.

Wang, W.W., Spurdle, A.B., Kolachana, P., Bove, B., Modan, B., Ebbers, S.M., Suthers, G., Tucker, M.A., Kaufman, D.J., Doody, M.M., Tarone, R.E., Daly, M., Levavi, H., Pierce, H., Chetrit, A., Yechezkel, G.H., Chenevix-Trench, G., Offit, K., Godwin, A.K., Struewing, J.P. A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers. Cancer Epidemiol. Biomark. Prev. 10:955-960, 2001.