Our lab is currently addressing the regulation of Notch signaling during Drosophila nervous system development using molecular genetics, live cell imaging, biochemistry and protein structure approaches. Examples of current projects include:
- Mechanistic analysis of the tumor suppressor genes in Notch signaling and polarity
- Reprogramming cell stem and progenitor cell fates in the Drosophila nervous system
- Role of extracellular cues in controlling Notch signaling in asymmetrically dividing cells
- Please contact Dr. Roegiers for further details on these or other potential projects