Faculty Summaries
Vasily M. Studitsky, PhD
Vasily M. Studitsky, PhD
Professor
  • Co-Leader, Cancer Epigenetics
Vasily.Studitsky@fccc.edu
Office Phone: 215-728-7014
Office: W209
Vasily M. Studitsky, PhD, Principal Investigator

Education

  • MS, Biochemistry, Moscow State University, 1984
  • PhD, Biochemistry, Institute of Molecular Biology, 1988
Olga Studitskaia (Kulaeva) , PhD, Associate Research Professor
Olga Studitskaia (Kulaeva)

Education

  • MS, Biology, Moscow State University, Moscow, Russia, 1984
  • PhD, Biochemistry, Moscow State University, Moscow, Russia, 1992

Research Interests

During last 10 years my interests have been mostly focused on the molecular mechanisms of transcription in chromatin. During my postdoctoral training in laboratories of L. Lutter (Henry Ford Hospital) and M. Tainsky (Wayne State University-SOM) I have gained experience with in vivo analysis and genomics of transcriptional regulation, respectively. After joining Studitsky laboratory on 2003, I complemented my previous experience with numerous in vitro approaches (biochemical, fluorescent, single particle, structural and computational modeling). Transcription is the first step in gene expression; the majority of genes are regulated at the levels of transcription initiation and/or elongation. Our research concentrates on analysis of the mechanisms and regulation of initiation and elongation of transcription by eukaryotic RNA polymerases using highly purified in vitro systems and complementary approaches in vivo.

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Artem V Demidenko, PhD, Postdoctoral Associate
Artem V. Demidenko, PhD

Education

Research Interests

Mechanism and regulation of transcript elongation in chromatin. Mechanisms of action of different nuclear protein factors during transcription through chromatin. Involvement of this proteins in oncogenesis and aging. Different modern methods for investigation of transcript elongation: time-resolved rapid-quench kinetic analysis, FRET techniques, single-molecule in vitro assays, etc. Integration of different data types in mathematical model.

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Han-Wen Chang , MS, Graduate Student
Han-Wen Chang, MS

Education

Research Interests

Mechanism of transcription through a nucleosome, especially the structural analysis of key intermediates. In addition, I also study the mechanism of replication through a nucleosome in vitro by kinetic methods and nucleosome fate.

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Ekaterina Nizovtseva, MS, Graduate Student
Ekaterina Nizovtseva, MS

Education

Research Interests

Mechanism of enhancer-promoter communication.

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Elena Kotova, MS, Technical Specialist
Elena Kotova

Education

Research Interests

Mechanism of transcription through nucleosomes and factors affecting it

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Anastasia Chupyrkina, PhD, Postdoctoral Associate
Anastasia Chupyrkina

Education

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