Faculty Summaries
Anthony T Yeung, PhD
Anthony Yeung, PhD
Associate Professor
Anthony.Yeung@fccc.edu
Office Phone: 215-728-2488
Fax: 215-728-3647

Recent Publications

  • Patel BB, Li XM, Dixon MP, Blagoi EL, Nicolas E, Seeholzer SH, Cheng D, He YA, Coudry RA, Howard SD, Riddle DM, Cooper HC, Boman BM, Conrad P, Crowell JA, Bellacosa A, Knudson A, Yeung AT, Kopelovich L. APC +/- alters colonic fibroblast proteome in FAP. Oncotarget. 2011 Mar;2(3):209-8. Pubmed - in process.
  • Capo-chichi CD, Smedberg JL, Rula ME, Nicolas E, Yeung AT, Adamo RF, Frolov AE, Godwin AK, and Xu XX. Alteration of differentiation potentials by modulating GATA transcription factors in murine embryonic stem cells. Stem Cells International. 2010 May 11;2010:602068.
  • Menges CW, Chen Y, Mossman BT, Chernoff J, Yeung AT, Testa JR. A Phosphotyrosine Proteomic Screen Identifies Multiple Tyrosine Kinase Signaling Pathways Aberrantly Activated in Malignant Mesothelioma. Genes Cancer 2010.1(5):493-505.
  • Bellacosa A, Godwin AK, Peri S, Devarajan K, Caretti E, Vanderveer L, Bove B, Slater C, Zhou Y, Daly M, Howard S, Campbell K, Nicolas E, Yeung AT, Clapper ML, Crowell JA, Lynch HT, Ross E, Kopelovich L, Knudson AG. Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations. Cancer Prev Res. 2010; 3:48-61.
  • Ke E, Patel BB, Liu T, Li XM, Haluszka O, Hoffman J, Ehya H, Young NA, Watson JC, Weinberg D, Nguyen M, Cohen SJ, Meropol NJ, Litwin S, Tokar JL, Yeung AT. Proteomic analyses of pancreatic cyst fluids. Pancreas. 2009;38:e33-42.
  • Yeung AT, Patel BB, Li XM, Seeholzer SH, Coudry RA, Cooper HS, Bellacosa A, Boman BM, Zhang T, Litwin S, Ross EA, Conrad P, Crowell JA, Kopelovich L, Knudson A. One-hit effects in cancer: Altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res. 2008;68:7579-86.
  • Patel BB, He YA, Li X, Frolov A, Vanderveer L, Slater C, Schilder RJ, Von Mehren M, Godwin AK, Yeung AT. Molecular mechanisms of action of imatinib mesylate in human ovarian cancer: a proteomic analysis. Cancer Genomics Proteomics. 2008;5(3-4):137-49.
  • Yeung AT, Patel BB, Li XM, Seeholzer SH, Coudry RA, Cooper HS, Bellacosa A, Boman BM, Zhang T, Litwin S, Ross EA, Conrad P, Crowell JA, Kopelovich L, Knudson A. One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res. 2008 Sep 15;68(18):7579-86.
  • Chen YB, Yeung A. Solid-phase extraction pipette tip sample preparation for membrane protein intact mass analysis by MALDI-MS. Lc Gc North America. 2007 Jun;:96-8.
  • Patel BB, Li XM, Dixon MP, Blagoi EL, Seeholzer SH, Chen Y, Miller CG, He YA, Tetruashvily M, Chaudhry AH, Ke E, Xie J, Cooper H, Bellacosa A, Clapper ML, Boman BM, Zhang T, Litwin S, Ross EA, Conrad P, Crowell JA, Kopelovich L, Knudson A, Yeung AT. Searchable high-resolution 2D gel proteome of the human colon crypt. J Proteome Res. 2007 Jun;6(6):2232-8.
  • Pimkin M, Caretti E, Canutescu A, Yeung JB, Cohn H, Chen Y, Oleykowski C, Bellacosa A, Yeung AT. Recombinant nucleases CEL I from celery and SP I from spinach for mutation detection. BMC Biotechnol. 2007;7:29.
  • Pimkin M, Miller CG, Blakesley L, Oleykowski CA, Kodali NS, Yeung AT. Characterization of a periplasmic S1-like nuclease coded by the Mesorhizobium loti symbiosis island. Biochem Biophys Res Commun. 2006 Apr;343(1):77-84.
  • Caslini C, Capo-chichi CD, Roland IH, Nicolas E, Yeung AT, Xu XX. Histone modifications silence the GATA transcription factor genes in ovarian cancer. Oncogene. 2006;25:5446-61.
  • Yeung A, Hattangadi D, Blakesley L, Nicolas E. Enzymatic mutation detection technologies. Biotechniques. 2005 May;38(5):749-58.
  • Li XM, Patel BB, Blagoi EL, Patterson MD, Seeholzer SH, Zhang T, Damle S, Gao Z, Boman B, Yeung AT. Analyzing alkaline proteins in human colon crypt proteome.[erratum appears in J Proteome Res. 2004 Nov-Dec;3(6):1300 Note: Seehozer, Steven H [corrected to Seeholzer, Steven H]]. Journal of Proteome Research. 2004 Jul-Aug;3(4):821-33.
  • Turner DP, Yeung AT, Bellacosa A. Ultraviolet irradiation of cells. Methods Mol Biol. 2004;285:133-7.
  • Yeung AT, Holloway BP, Adams PS, Shipley GL. Evaluation of dual-labeled fluorescent DNA probe purity versus performance in real-time PCR. Biotechniques. 2004 Feb;36(2):266-70, 272, 274-5.
  • Muthu S, Pisarcik DA, Bao R, Yeung AT, Hamilton TC. Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res. 2003;63:1311-6.
  • Bahrami AR, Dickman MJ, Matin MM, Ashby JR, Brown PE, Conroy MJ, Fowler GJ, Rose JP, Sheikh QI, Yeung AT, Hornby DP. Use of fluorescent DNA-intercalating dyes in the analysis of DNA via ion-pair reversed-phase denaturing high-performance liquid chromatography. Anal Biochem. 2002 Oct 15;309(2):248-52.
  • Dickstein R, Hu XJ, Yang J, Ba L, Coque L, Kim DJ, Cook DR, Yeung AT. Differential expression of tandemly duplicated Enod8 genes in Medicago. Plant Science. 2002 Aug;163(2):333-43.
  • Colbert T, Till BJ, Tompa R, Reynolds S, Steine MN, Yeung AT, McCallum CM, Comai L, Henikoff S. High-throughput screening for induced point mutations. Plant Physiol. 2001 Jun;126(2):480-4.
  • Gunthorpe M, Fox JW, Hager KM, Lilley KS, Scaringe S, Yeung AT. Use of mass spectrometry, capillary electrophoresis, and gel electrophoresis for quality analysis of synthetic oligonucleotides: perspectives from the ABRF Nucleic Acid Research Group. J Biomol Tech. 2001 2001;12:16-24.
  • Sokurenko EV, Tchesnokova V, Yeung AT, Oleykowski CA, Trintchina E, Hughes KT, Rashid RA, Brint JM, Moseley SL, Lory S. Detection of simple mutations and polymorphisms in large genomic regions. Nucl Acids Res. 2001 November 15, 2001;29(22):e111.