BASIC SCIENCE

THE ROLE OF THE EPSTEIN-BARR AND HUMAN IMMUNODEFICIENCY VIRUSES IN AIDS LYMPHOMA
SUSAN M. ASTRIN, Ph.D.

RECOMBINATION AND EXPRESSION OF ANTIGEN RECEPTOR GENES
MELVIN J. BOSMA, Ph.D.

GATA-4/5/6 GENE REGULATION AND HEART DEVELOPMENT
JOHN BURCH, Ph.D.

SIGNAL TRANSDUCTION BY INHIBITORY RECEPTORS ON HUMAN NATURAL KILLER CELLS
Kerry S. Campbell, Ph.D.

ROLE OF PROTEIN PHOSPHORYLATION IN ADHESION-DEPENDENT SIGNALING PATHWAYS
JONATHAN CHERNOFF, M.D., Ph.D.

MOLECULAR MECHANISMS GOVERNING EUKARYOTIC DNA REPLICATION AND CELL CYCLE PROGRESSION
THOMAS R. COLEMAN, Ph.D.

COMPUTATIONAL STRUCTURAL BIOLOGY: STRUCTURE PREDICTION, ANALYSIS, AND BIOINFORMATICS
ROLAND L. DUNBRACK, Jr., Ph.D.

PROTEIN DNA INTERACTIONS
JAN FENG, Ph.D.

STRUCTURAL STUDIES IN ENZYME MECHANISMS AND IN CHEMICAL CARCINOGENESIS AND MUTAGENESIS
JENNY PICKWORTH GLUSKER, D.Phil., D.Sc.

HUMAN/YEAST COMPLEMENTATION APPROACHES TO STUDY OF ONCOGENIC SIGNALLING
ERICA A. GOLEMIS, Ph.D.

FETAL AND ADULT B LYMPHOCYTE DIFFERENTIATION
RICHARD R. HARDY, Ph.D.

LYMPHOCYTE DEVELOPMENT AND DIFFERENTIATION INTO MEMORY
KYOKO HAYAKAWA, M.D., Ph.D.

HOW ENZYMES WORK
EILEEN K. JAFFE, Ph.D.

T CELL DEVELOPMENT AND SIGNAL TRANSDUCTION
DIETMAR J. KAPPES, Ph.D.

STRUCTURE AND FUNCTION OF ENZYMES
GEORGE D. MARKHAM, Ph.D.

HEPATITIS VIRUSES AND LIVER CANCER
WILLIAM S. MASON, Ph.D.

MELANOMA DEVELOPMENT AND PROGRESSION IN TRANSGENIC MOUSE MODELS
BEATRICE MINTZ, Ph.D.

DEVELOPMENTAL TIMING AND TRANSLATIONAL REGULATION IN THE NEMATODE CAENORHABDITIS ELEGANS
ERIC G. MOSS, Ph.D.

REGULATION OF GENE EXPRESSION
ROBERT P. PERRY, Ph.D.

PATHOGENESIS OF NEUROTROPIC VIRAL INFECTIONS
GLENN F. RALL, Ph.D.

PROTEIN FOLDING, DYNAMICS AND FUNCTION
HEINRICH RODER, Ph.D.

REPLICATION AND PATHOGENESIS OF HEPATITIS B VIRUSES
CHRISTOPH SEEGER, Ph.D.

MOLECULAR BIOLOGY OF RETROVIRUSES
ANNA MARIE SKALKA, Ph.D.

GENETIC CONTROL OF MEIOTIC DEVELOPMENT IN YEAST
RANDY STRICH, Ph.D.

HEPATITIS DELTA VIRUS
JOHN M. TAYLOR, Ph.D.

DEVELOPMENTAL REGULATION OF T CELL ANTIGEN RECEPTOR EXPRESSION AND FUNCTION
David L. Wiest, Ph.D.

REPLICATION AND ORGANIZATION OF EUKARYOTIC GENOMIC DNA
HONG YAN, Ph.D.

CELLULAR MECHANISMS THAT MAINTAIN STABILITY OF THE HUMAN GENOME
TIM J. YEN, Ph.D.

DNA REPAIR AND MUTATION DETECTION
ANTHONY T. YEUNG, Ph.D.

MEDICAL SCIENCE

NURSING RESEARCH
ANDREA M. BARSEVICK, R.N., D.N.Sc.

STRUCTURE AND FUNCTION OF MAMMALIAN TELOMERES
DOMINIQUE BROCCOLI, Ph.D.

IN VIVO STUDIES OF METABOLISM AND METABOLIC PERTURBATIONS BY NUCLEAR MAGNETIC RESONANCE
TRUMAN R. BROWN, Ph.D.

MECHANISMS OF TUMOR RADIORESISTANCE
J. DONALD CHAPMAN, Ph.D.

SURGICAL ONCOLOGY
BURTON L. EISENBERG, M.D., F.A.C.S.

ONCOLOGICAL GASTROENTEROLOGY PROGRAM
HAROLD FRUCHT, M.D.

PHARMACOKINETICS AND DRUG DELIVERY
JAMES M. GALLO, Ph.D.

THE MOLECULAR GENETICS OF FAMILIAL, HEREDITARY, AND SPORADIC FORMS OF BREAST AND OVARIAN CANCER
ANDREW K. GODWIN, Ph.D.

BREAST CANCER RESEARCH
LORI J. GOLDSTEIN, M.D.

THREE DIMENSIONALIN VIVO METABOLIC IMAGING IN THE HUMAN BRAIN
ODED GONEN, Ph.D.

THE BIOLOGY OF OVARIAN CANCER
THOMAS C. HAMILTON, Ph.D.

RADIATION ONCOLOGY
GERALD E. HANKS, M.D.

TUBEROUS SCLEROSIS, LYMPHANGIOMYOMATOSIS, AND POLYCYSTIC KIDNEY DISEASE
ELIZABETH PETRI HENSKE, M.D.

SYSTEMIC THERAPY OF PROSTATE CANCER
GARY R. HUDES, M.D.

MOLECULAR PATHOLOGY OF TUMOR PROGRESSION
ANDRES J.P. KLEIN-SZANTO, M.D.

SIGNAL TRANSDUCTION BY TYROSINE KINASES/MOLECULAR MECHANISMS OF CELLULAR RESISTANCE TO CYTOTOXIC DRUGS
GARY D. KRUH, M.D., Ph.D.

MOLECULAR MECHANISMS OF DNA REPAIR IN EUKARYOTES
YOSHIHIRO MATSUMOTO, Ph.D.

MEDICAL ONCOLOGY: CLINICAL TRIALS RESEARCH
LOUIS M. WEINER, M.D.

GASTROINTESTINAL CANCER PROGRAM
NEAL J. MEROPOL, M.D.

Elucidation of the p53-dependent programmed cell death pathway
MAUREEN E. MURPHY, Ph.D.

TUMOR DIAGNOSTIC LABORATORIES
ARTHUR S. PATCHEFSKY, M.D.

REGULATION OF SIGNAL TRANSDUCTION AND CHANGES IN PATTERNS OF GENE EXPRESSION IN BREAST AND OVARIAN CANCER
CHRISTOS PATRIOTIS, Ph.D.

THE ROLE OF PHARMACOGENETICS IN CANCER THERAPY, PREVENTION, AND RISK
REBECCA B. RAFTOGIANIS, Ph.D.

BREAST CANCER PREVENTION
IRMA H. RUSSO, M.D.

BREAST CANCER RESEARCH LABORATORY
JOSE RUSSO, M.D.

RADIATION PHYSICS
TIMOTHY E. SCHULTHEISS, Ph.D.

SURGICAL RESEARCH
ELIN R. SIGURDSON, M.D., Ph.D.

HEMATOLOGY AND HEMATOLOGIC MALIGNANCIES
MITCHELL R. SMITH, M.D., Ph.D.

TUMOR GENETICS/MOLECULAR CHARACTERIZATION OF THE AKT2 ONCOGENE
JOSEPH R. TESTA, Ph.D.

CANCER DRUG RESISTANCE
KENNETH D. TEW, Ph.D., D.Sc.

THE BIOCHEMISTRY AND MOLECULAR GENETICS OF PROSTATE CANCER PROGRESSION
JAMES V. TRICOLI, Ph.D.

TARGETED THERAPY
LOUIS M. WEINER, M.D.

POPULATION SCIENCE

GENETIC EPIDEMIOLOGY OF PROSTATE CANCER AND BREAST CANCER
AGNES B. BAFFOE-BONNIE, M.D., M.P.H., Ph.D.

GENETICS AND FUNCTION OF DNA MISMATCH REPAIR
ALFONSO BELLACOSA, M.D.

CANCER INFORMATION SERVICE
LINDA FLEISHER, M.P.H.

PRECLINICAL CHEMOPREVENTION: BIOMARKERS OF CANCER RISK AND CHEMOPREVENTIVE RESPONSE
MARGIE L. CLAPPER, Ph.D.

GENETIC RISK FOR CANCER: A MODEL FOR CANCER CONTROL
MARY B. DALY, M.D., Ph.D.

NATURAL HISTORY OF HEPATITIS B INFECTION
ALISON A. EVANS, Sc.D.

GENETIC AND MOLECULAR BASIS OF LEUKEMIA AND MAMMARY CANCER METASTASIS
KENT W. HUNTER, Ph.D.

ANALYSIS OF FUNCTIONAL VARIATION IN HUMAN METABOLIC GENES
WARREN KRUGER, Ph.D.

MATHEMATICAL AND STATISTICAL MODELS FOR RESEARCH
SAMUEL LITWIN, Ph.D.

EPIDEMIOLOGY, PATHOGENESIS, AND PREVENTION OF HEPATITIS B VIRUS INFECTION AND LIVER CANCER
W. THOMAS LONDON, M.D.

SOCIAL AND COGNITIVE INFLUENCES ON ADAPTATION TO CANCER
SHARON MANNE, Ph.D.

PSYCHOSOCIAL AND BEHAVIORAL MEDICINE PROGRAM
SUZANNE M. MILLER, Ph.D.

FOX CHASE NETWORK
PAUL F. ENGSTROM, M.D.

STATISTICAL METHODS IN CLINICAL TRIALS AND GENETIC EPIDEMIOLOGY
ANDRÉ ROGATKO, Ph.D.

INTERVENTIONS TO PREVENT EPITHELIAL DEGENERATION TO CARCINOMA
EDWARD SAUTER, M.D.

CLINICAL CHEMOPREVENTION TRIALS
CHRISTINE E. SZARKA, M.D.

FACILITIES

FOX CHASE BREAST CANCER TISSUE RESOURCE
JOSE RUSSO, .FD.

CELL CULTURE FACILITY
MARY ANN SELLS, Ph.D.

CELL IMAGING FACILITY
KENNETH D. TEW, Ph.D.

AUTOMATED DNA SEQUENCING FACILITY
RICHARD R. HARDY, Ph.D.

ELECTRON MICROSCOPE FACILITY
MICHAL JARNIK, Ph.D.

EXPERIMENTAL HISTOPATHOLOGY SERVICE
ANDRES J.P. KLEIN-SZANTO, M.D.

THE FANNIE E. RIPPEL BIOTECHNOLOGY FACILITY
ANTHONY T. YEUNG, Ph.D.

HYBRIDOMA FACILITY
MELVIN J. BOSMA, Ph.D.

INSTRUMENT SHOP FACILITY
JOHN W. MOELLER

IRRADIATION FACILITY
J. DONALD CHAPMAN, Ph.D.

LABORATORY ANIMAL FACILITY
TIMOTHY W. POOLE, Ph.D.

MEDICAL/ADMINISTRATIVE COMPUTER FACILITY
FLORENCE TANNER

MEDICAL INFORMATION MANAGEMENT PROGRAM
MICHAEL A. BOOKMAN, M.D.

NMR MICRO-IMAGING FACILITY
HEINRICH RODER, Ph.D.

ORGANIC SYNTHESIS LABORATORY
JENNY PICKWORTH GLUSKER, D.Phil., D.Sc.

PROTOCOL MANAGEMENT OFFICE
MICHAEL A. BOOKMAN, M.D.

RESEARCH COMPUTING SERVICES
FRANK J. MANION, M.S.

RESEARCH CYTOGENETICS LABORATORY
JOSEPH R. TESTA, Ph.D.

RESEARCH FLOW CYTOMETRY AND CELL SORTING FACILITY
RICHARD R. HARDY, Ph.D.

RESEARCH SECRETARIAL SERVICES
MARGARET H. EINENKEL

SPECIAL SERVICES FOR GRAPHIC AND AUDIOVISUAL ARTS
RICHARD BOMZE, B.F.A.

SPECTROSCOPY SUPPORT FACILITY
HEINRICH RODER, Ph.D.

STATISTICAL CONSULTING SERVICE
ANDRÉ ROGATKO, Ph.D.

TRANSGENIC MOUSE FACILITY
DIETMAR J. KAPPES, Ph.D.

ACKNOWLEDGMENTS

Acknowledgments

Fox Chase Cancer Center

Scientific Report 1998