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2001 Scientific Report
Basic Science
Institute for Cancer Research
Forty-Sixth Scientific Report
Video introduction to Basic Science at Fox Chase
(Requires RealPlayer®)
Biomolecular Structure and Function
- Structural Studies in Enzyme Mechanisms and in Chemical Carcinogenesis and Mutagenesis
Jenny Pickworth Glusker, DPhil, DSc - Protein Structure Prediction in Biology and Medicine
Roland L Dunbrack, Jr, PhD - How Enzymes Work
Eileen K Jaffe, PhD - Structure and Function of Enzymes
George D Markham, PhD - Protein Folding, Structure and Function
Heinrich Roder, PhD - DNA Repair and Mutations
Anthony T Yeung, PhD
Cellular and Developmental Biology
- Gene Regulatory Mechanisms, Cell Differentiation, and Organogenesis
Kenneth S Zaret, PhD - GATA-4/5/6 Gene Regulation and Heart Development
John Burch, PhD - Novel Translational Regulators in Animal Development
Eric G. Moss, PhD - Regulation of Gene Expression
Robert P Perry, PhD - Genetics of Pigmentation:From Neural Crest to Melanocytes
Myung K Shin, PhD - Regulation of Meiotic Development in Yeast
Randy Strich, PhD - Analysis of RECQ Family of Helicases:
A New Paradigm for Genome Duplication
Hong Yan, PhD - Molecular Mechanisms that Maintain Genome Stability in Human Cells
Tim J Yen, PhD
Immunobiology
- Fetal and Adult B Lymphocyte Differentiation
Richard R Hardy, PhD - Recombination and Expression of Antigen Receptor Genes
Melvin J Bosma, PhD - Signal Transduction by Receptors on Human Natural Killer Cells
Kerry S Campbell, PhD - Self-Antigen and Immune System Development
Kyoko Hayakawa, MD, PhD - T Cell Development and Signal Transduction
Dietmar J Kappes, PhD - Control of T Lymphocyte Development by Antigen Receptors
David L Wiest, PhD
Tumor Cell Biology
- Role of Protein Phosphorylation in Adhesion-Dependent Signaling Pathways
Jonathan Chernoff, MD, PhD - Regulation of DNA Synthesis, Histone Synthesis and Chromatin Assembly in S-Phase
Peter D Adams, PhD - Molecular Mechanisms Governing Eukaryotic DNA Replication and Cell Cycle Progression
Thomas R Coleman, PhD - Analysis and Manipulation of Signal Transduction Networks
Erica A Golemis, PhD - Mitotic Chromosome Structure and Segregation in Yeast
Vincent Guacci, PhD - Melanoma Progression and Therapy in Transgenic Mouse Models
Beatrice Mintz, PhD
Virology
- Hepatitis Delta Virus
John M Taylor, PhD - Hepatitis Viruses and Liver Cancer
William S Mason, PhD - Pathogenesis of Neurotropic Viral Infections
Glenn F Rall, PhD - Replication and Pathogenesis of Hepatitis Viruses
Christoph Seeger, PhD - Mechanisms of MHC Class I Antigen Presentation and Cytotoxic T Lymphocyte Immunity
Luis J Sigal, DVM, PhD - Molecular Biology of Retroviruses
Anna Marie Skalka, PhD