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2002 Scientific Report
Basic Science
Institute for Cancer Research
Forty-Seventh Scientific Report
Video introduction to Basic Science at Fox Chase
(Requires RealPlayer®)
Biomolecular Structure and Function
- Protein Folding, Structure and Function
Heinrich Roder, PhD - Protein Structure Prediction in Biology and Medicine
Roland L Dunbrack, Jr, PhD - Structural Studies of Enzyme Mechanisms and of Chemical Carcinogenesis and Mutagenesis
Jenny Pickworth Glusker, DPhil, DSc - How Enzymes Work
Eileen K Jaffe, PhD - Structure and Function of Enzymes
George D Markham, PhD - DNA Repair and Mutations
Anthony T Yeung, PhD
Cellular and Developmental Biology
- Gene Regulatory Mechanisms, Cell Differentiation, and Organogenesis
Kenneth S Zaret, PhD - GATA-4/5/6 Gene Regulation and Heart Development
John Burch, PhD - Regulation of the Transcription of Mammalian Ribosomal Protein Genes
Robert P Perry, PhD - Endothelin Receptor-B (EDNRB) and Neural Crest Migration
Myung K Shin, PhD - Regulation of Meiotic Development in Yeast
Randy Strich, PhD - Analysis of RECQ Family of Helicases:
A New Paradigm for Genome Duplication
Hong Yan, PhD - Molecular Mechanisms that Maintain Genome Stability in Human Cells
Tim J Yen, PhD
Immunobiology
- Fetal and Adult B Lymphocyte Differentiation
Richard R Hardy, PhD - B Cell Differentiation in Immunoglobulin Transgenic Scid Mice
Melvin J Bosma, PhD - Signal Transduction by Receptors on Human Natural Killer Cells
Kerry S Campbell, PhD - Self-Antigen and Immune System
Kyoko Hayakawa, MD, PhD - T Cell Development and Signal Transduction
Dietmar J Kappes, PhD - Control of T Lymphocyte Development by Antigen Receptors
David L Wiest, PhD
Tumor Cell Biology
- Role of Protein Phosphorylation in Adhesion-Dependent Signaling Pathways
Jonathan Chernoff, MD, PhD - Histone Synthesis, Chromatin Assembly and Genome Stability in S-Phase
Peter D Adams, PhD - A Study of 3D-Adhesions, In Vivo Signaling Dynamics, and Cancerous Microenvironmental Analyses
Edna Cukierman, PhD - Connecting Cell Shape and Cell Division Controls in Cancer
Erica A Golemis, PhD - Mitotic Chromosome Structure and Segregation in Yeast
Vincent Guacci, PhD - Melanoma Progression and Therapy in Transgenic Mouse Models
Beatrice Mintz, PhD
Virology
- Hepatitis Delta Virus
John M Taylor, PhD - Exploring the Life Cycle of Hepatitis C Virus and Other Members of the Flaviviridae Family
Sven-Erik Behrens, PhD - Hepatitis Viruses and Liver Cancer
William S Mason, PhD - Pathogenesis of Neurotropic Viral Infections
Glenn F Rall, PhD - Replication and Pathogenesis of Hepatitis Viruses
Christoph Seeger, PhD - Mechanisms of MHC Class I Antigen Presentation and Cytotoxic T Lymphocyte Immunity
Luis J Sigal, DVM, PhD - Molecular Biology of Retroviruses
Anna Marie Skalka, PhD