Faculty Summaries
Patchefsky
Arthur S Patchefsky, MD
Professor
  • Chairman, Pathology

Publications

  • Meyers MO, Brown TA, Young N, Giles LR, Sigurdson ER, Hoffman JP, Ross E, Boraas MC, Eisenberg BL, Torosian MH. Sentinel lymph node metastasis in breast cancer. Is completion axillary dissection mandated in all patients? Breast J. Forthcoming 2009
  • Patchefsky AS, Ehya H, Wu H. Localized diseases of the bronchi and lung. In Principles and Practice of Surgical Pathology and Cytopathology, Fourth Edition, edited by S. Silverberg. Churchill Livingstone, New York. Forthcoming 2009.
  • Sauter ER, Ehya H, Klein-Szanto A, Wagner-Mann C, MacGibbon B. Fiberoptic ductoscopy findings in women with and without spontaneous nipple discharge. Cancer. 2005 Mar 1;103(5):914-21.
  • Wu H, Barusevicius A, Babb J, Klein-Szanto A, Godwin A, Elenitsas R, Gelfand JM, Lessin S, Seykora JT. Pleiotrophin expression correlates with melanocytic tumor progression and metastatic potential. J Cutan Pathol. 2005 Feb;32(2):125-30.
  • Hughes J, Young NA, Wilbur DC, Renshaw AA, Mody DR. Fine-Needle aspiration of pulmonary hamartoma: A common source of false-positive diagnoses in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology. Arch Pathol Lab Med. 2005 Jan;129(1):19-22.
  • Kucher C, Zhang PJ, Pasha T, Elenitsas R, Wu H, Ming M, Elder DE, Xu X. Expression of Melan-A and Ki-67 in desmoplastic melanoma and desmoplastic nevi. Am J Dermatopathol. 2004 Dec;26(6):452-7.
  • Al-Saleem T, Al-Mondhiry H. Immunoproliferative small intestinal disease (IPSID); a model for mature B-cell neoplasms. Blood. Epub, Nov. 12, 2004.
  • Al-Saleem T, Cairns P, Dulaimi EA, Feder M, Testa JR, Uzzo RG. The genetics of renal oncocytosis; a possible model for neoplastic progression. Cancer Genet Cytogenet. 2004;52(1):23-28.
  • Cooper HS. Neoplasms of the intestine. In Sternberg's Diagnostic Surgical Pathology, Fourth Edition, edited by S.E. Mills. Lippincott Williams & Wilkins, Philadelphia, pp. 1543-1601, 2004.
  • Dulaimi E, Hilinck J, Ibanez de Caceres I, Al-Saleem T, Cairns P. Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients. Clin Cancer Res. 2004;10:6189-93.
  • Dulaimi E, Ibanez de Caceres I, Uzzo RG, Al-Saleem T, Greenberg RE, Polascik TJ, Babb JS, Grizzle WE, Cairns P. Promoter hypermethylation profile of kidney cancer. Clin Cancer Res. 2004;10:3972-79.
  • Dulaimi E, Uzzo RG, Greenberg RE, Al-Saleem T, Cairns P. Detection of bladder cancer in urine by a tumor suppressor gene hypermethylation panel. Clin Cancer Res. 10 200;(6);1887-93.
  • Edwards R, Ward MR, Wu H, Medina CA, Brose MS, Volpe P, Nussen-Lee S, Haupt HM, Martin A, Herlyn M, Lessin SR, Weber BL. Absence of BRAF mutations in UV-protected mucosal melanomas. J Med Genet. 2004;41(4):270-2.
  • Ibanez de Caceres I, Battagli C, Esteller M, Herman JG, Dulaimi E, Edelson MI, Bergman C, Ehya H, Eisenberg BL, Cairns P. Tumor cell specific BRCA1 and RASSF1A hypermethylation in serum, plasma and peritoneal fluid from ovarian cancer patients. Cancer Res. 2004;64:6476-81.
  • Krassenstein R, Sauter E, Al-Saleem E, Battagli C, Ehya H, Klein-Szanto A, Cairns P. Detection of breast cancer in nipple aspirate fluid by hypermethylation. Clin. Cancer Res. 2004;10:28-32.
  • Mueller TJ, Wu H, Greenberg RE, Hudes G, Topham N, Lessin SR, Uzzo RG. Cutaneous metastases from genitourinary malignancies. Urology. 2004;63(6):1021-106.
  • Patchefsky AS. Nonneoplastic pulmonary disease. In Sternberg's Diagnostic Surgical Pathology, Fourth Edition, edited by S.E. Mills. Lippincott Williams & Wilkins, Philadelphia, pp. 1111-1172, 2004.
  • Pollack A, DeSilvio M, Khor LY, Li R, Al-Saleem TI, Hammond ME, Venkatesan V, Lawton CA, Roach M 3rd, Shipley WU, Hanks GE, Sandler HM. Ki-67 staining is a strong predictor of distant metastasis and mortality for men with prostate cancer treated with radiotherapy plus androgen deprivation: Radiation Therapy Oncology Group Trial 92-02. J Clin Oncol. 2004;22(11):2133-40.
  • Renshaw AA, Schulte MA, Plott E, Dubray-Bernstein B, Cobb CJ. Lozano RL, Neal MH, Hughes JH, Young NA, Prey M. Cytologic features of high-grade squamous intraepithelial lesion in ThinPrep Papanicolaou test slides: Comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology. Arch Pathol Lab Med. 2004;128:746-8.
  • Renshaw AA, Young NA, Birdsong GG, Styer PE, Davey DD, Mody DR, Colgan TJ. Comparison of performance of conventional and ThinPrep gynecologic preparations in the College of American Pathologists Gynecologic Cytology Program. Arch Pathol Lab Med. 2004;128:17-22.
  • Sauter ER, Klein-Szanto A, Ehya H, MacGibbon B. Ductoscopic cytology and image analysis to detect breast cancer. Cancer. 2004;101:1283-92.
  • Sauter ER, Ehya H, Schlatter L, MacGibbon L. Ductoscopic cytology to detect breast cancer. Cancer J. 2004;10:33-41.
  • Subhi A, Tang B, Salsara B, Altomare D, Testa JK, Copper HS, Hoffman JP, Meropol NJ, Kruger WD. Loss of methylthiodenosine phosphylase and elevated ornithine dicarboxylase is common in pancreatic cancer. Clin Cancer Res. 2004;10:7290-6.
  • Upson JS, Stoyanova R, Cooper HS, Patriotis C, Ross EA, Boman B, Clapper MI, Knudson AG, Bellacosa A. Optimized procedures for microarray analysis of histologic specimens processed by laser capture microdissection. J Cell Physiol. 2004;201:366-73.
  • Wu H, Barusevicius A, Lessin SR. Granuloma annulare with a mycosis fungoides-like distribution and palisaded granulomas of CD68-Positive histiocytes. J Am Acad Dermatol. 2004;51(1):39-44.
  • Young NA, Bibbo M, Buckner S, Colgan T, Prey M. Non-neoplastic findings. In The Bethesda System for Reporting Cervical/Vaginal Cytologic Diagnoses, Second Edition, edited by D. Solomon and R. Nayar. Springer-Verlag, New York, pp. 21-56, 2004.
  • Young NA, Ehya H. Grading follicular lymphoma. The Achilles heel of diagnosis by cytology. Acta Cytol. 2004;48:117-8.
  • Al-Saleem TI. Re: Lin and Gray - Immunoproliferative small intestinal disease. Am J Gastroenterol. 2003;98:501.
  • Battagli C, Uzzo RG, Dulaimi E, Ibanez De Caceres I, Krassenstein R, Al-Saleem T, Greenberg RE, Cairns P. Promoter hypermethylation of tumor suppressor genes in urine from kidney cancer patients. Cancer Res. 2003;63:8695-9.
  • Chism DB, Hanlon AL, Troncoso P, Al-Saleem T, Horwitz EM, Pollack A. The Gleason score shift: score four and seven years ago. Int J Radiat Oncol Biol Phy. 2003;56:1241-7.
  • Ehya H, Patchefsky A. Bronchus-Associated Lymphoid Tissue (BALT) Lymphoma: Diagnosis by Fine Needle Aspiration Cytology and Flow Cytometry. Case Report and Review. Pathol Case Rev. 2003;8:267-274.
  • Ehya H, Young N. Cytologic approach to tumors of the tracheobronchial tree. Chest Surg Clin N Am. 2003;13:1-22.
  • Freedman GM, Anderson PR, Goldstein LJ, Hanlon AL, Cianfrocca ME, Millenson MM, von Mehren M, Torosian MH, Boraas MC, Nicolaou N, Patchefsky AS, Evers K. Routine mammography is associated with earlier stage disease and greater eligibility for breast conservation in breast carcinoma patients age 40 years and older. Cancer. 2003;98:918-25.
  • Moriarty AT, Young NA. The Four R's: Reactive/Repair, Reporting and Regulations. Diagn Cytopathol. 2003;29:1-3.
  • Patchefsky AS. Chapter 25, In Diagnostic Surgical Pathology, Fourth Edition, Nonneoplastic Pulmonary Disease, edited by S.S. Sternberg, Lippincott Williams & Wilkins, Philadelphia, 2003.
  • Patchefsky A, Burk M. Chapter 1, Pathology of Ovarian Tumors. In ACS Atlas of Oncology. edited by A Patchefsky, M Burk, BC Decker, Inc., Ontario, Canada, 2003.
  • Patchefsky A, Goldberg M. Unusual Bronchial Tumors. In Chest Surgery Clinics of North America, edited by A. Patchefsky, M. Goldberg, W.B. Saunders, Philadelphia, 2003.
  • Pollack A, DeSilvio M, Khor L, Li R, Al-Saleem T, Hammond M, Venkatesan V, Byhardt R, Hanks GE, Roach M, Shipley WU, Sandler HM. Ki-67 Staining is a strong predictor of patient outcome for prostate cancer patients treated with androgen deprivation plus radiotherapy: an analysis of RTOG 92-02. Int J Radiat Oncol Biol Phys. 2003;S200-S201.
  • Uzzo RG, Cairns P, Al-Saleem T, Hudes G, Haas N, Greenberg RE, Kolenko V. The basic biology and immunobiology of renal cell carcinoma: consideration for the clinician. Urol Clin North Am. 2003;30:423-36.
  • Wu H, Smith M, Millenson MM, Nicolaou N, Van Deerlin VM, Addya K, Lessin SR, Al-Saleem T. Contribution of flow cytometry in the diagnosis of cutaneous lymphoid lesions. J Invest Dermatol. 2003;121(6):1522-30.
  • Wu H, Stanley JR, Cotsarelis G. Desmoglein isotype expression in the hair follicle and its cysts correlates with type of keratinization and degree of differentiation. J Inv Dermatol. 2003;120:1052-57.
  • Zhu W, Qin W, Ehya H, Lininger J, Sauter E. Microsatellite changes in nipple aspirate fluid (NAF) and breast tissue from women with breast carcinoma or its precursors. Clin Cancer Res. 2003;9:3029-33.
  • Augsburger JJ, Correa ZM, Schneider S, Yassin RS, Robinson-Smith T, Ehya H, Trichopoulos N. Diagnostic transvitreal fine needle aspiration biopsy of small melanocytic choroidal tumors in nevus versus melanoma category. Trans Am Ophthalmol Soc. 2002100:225-32.
  • Duffy K, Al-Saleem T, Karbowniczek M, Ewalt D, Prowse A. Henske EP. Mutational analysis of the von Hippel Lindau gene in clear cell renal carcinomas from Tuberous Sclerosis Complex patients. Modern Pathol. 2002;15(3):205-10.
  • Frolov A, Prowse AH, Vanderveer L, Bove B, Wu H, Godwin AK. DNA array-based method for detection of large rearrangements in the BRCA1 gene. Genes Chromosomes Cancer 2002;35(3):232-41.
  • Patchefsky A. Nonproliferative and benign proliferative epithelial lesions. In Atlas of Breast Pathology, Chapter 6, edited by S. Silverberg. W.B. Saunders, Philadelphia, pp. 57-65, 2002.
  • Solomon D, Davey D, Kurman R, Moriarty A, O'Connor D, Prey M, Raab S, Sherman M, Wilbur D, Wright T, Young N. The 2001 Bethesda System: Terminology for reporting results of cervical cytology. JAMA. 2002;287:2114-9.
  • Wetherington RW, Cooper HS, Al-Saleem T, Ackerman DS, Adams-McDonnell R, Davis W, Ehya H, Patchefsky AS, Suder J, Young NA. Clinical Significance of performing immunohistochemistry on cases with previous diagnosis of cancer coming to a national comprehensive cancer center for treatment or second opinion. Am J Surg Pathol. 2002;26:1222-30.
  • Yang DH, Smith ER, Cohen C, Wu H, Patriotis C, Godwin AK, Hamilton TC, Xu X. Molecular events associated with dysplastic morphological transformation and initiation of ovarian tumorigenicity. Cancer. 2002;94(9):2380-92.
  • Wu H, Eleinstsas R, Zhang P, Elder DE. Merkel cell carcinoma. In Endocrine Pathology, Chapter 11, edited by Li, Volsi, and Asa. W.B. Saunders, Philadelphia, PA, 2002.
  • Young NA. Back to the negative pap test: Behind the scenes at Bethesda 2001. Diagn. Cytopathol. 2002;26:207-8.
  • Young NA, Mody DR, Davey DD. Misinterpretation of normal cellular elements in fine needle aspiration biopsies. Observations from the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytology. Arch Pathol Lab Med. 2002;126:670-5.
  • Young NA, Mody DR, Davey DD. Diagnosis and subclassification of breast carcinoma by fine needle aspiration biopsy: Results of the Interlaboratory Comparison Program in Non-Gynecologic Cytopathology. Arch Pathol Lab Med. 2002;126:1453-7.
  • Zimmerman RL, Burke M, Young NA, Solomides CC, Bibbo M. Diagnostic utility of Glut-1 and CA 15-3 for discriminating adenocarcinoma from hepatocellular carcinoma in liver tumors biopsies by fine needle aspiration. Cancer Cytopathol. 2002;96:53-57.
  • Zimmerman RL, Das KM, Bruke MA, Young NA, Solomides CC, Bibbo M. The clinical utility of the CAS-1 monoclonal antibody in identifying adenocarcinoma of the colon metastatic to the liver in fine needle aspiration tissue. Cancer. 2002;96:(6):370-3.
  • Chao C, Al-Saleem T, Brooks JJ, Rogatko A, Kraybill WG, Eisenberg B. Vascular endothelial growth factor and soft tissue sarcomas: tumor expression correlates with grade. Ann Surg Oncol. 2001;3:260-267.
  • Cooper HS, Everley L, Chang W-C, Pfeiffer G, Lee B, Murthy S, Clapper ML. The role of mutant Apc in the development of dysplasia and cancer in the mouse colitis model of Dextran Sulfate Sodium-induced colitis. Gastroenterology. 2001;121:1407-16.
  • Elias PM, Matsuyoshi N, Wu H, Lin C, Wang ZH, Brown BE, Stanley JR. Desmoglein isoform distribution affects stratum corneum structure and function. J Cell Biol. 153 2001;(2):243-9.
  • Honavar SG, Shields JA, Shields CL, Demirci H, Ehya H. Extramedullary plasmacytoma confined to the choroid. Am J Ophthalmol. 2001;131:277-8.
  • Jordan JJ, Hanlon AL, Al-Saleem T, Greenberg RE, Tricoli JV. Loss of the short arm of the Y chromosome in human prostate carcinoma. Cancer Genet Cytogenet. 2001;124:122-6.
  • Pingpank JF, Hoffman JP, Ross EA, Cooper HS, Meropol NJ, Freedman G, Pinover W, Le Voyer TE, Sasson AR, Eisenberg BL. Effect of pre-operative chemoradiation on surgical margin status of resected adenocarcinoma of the head of the pancreas. J Gastrointest Surg. 2001;5:121-30.
  • Sasson AR, Fowble B, Hanlon AL, Torosian MH, Freedman G, Boraas M, Sigurdson ER, Hoffman JP, Eisenberg BL, Patchefsky AS. Lobular carcinoma in situ increases the risk of local recurrence in selected patients with stages I and II breast cancer treated with conservative surgery and radiation. Cancer. 2001;91(10):1862-9.
  • Sauter ER, Ehya H, Mammen A, Klein G. Nipple aspirate cytology and pathologic parameters predict residual cancer and nodal involvement after excisional breast biopsy. Br J Cancer 2001;85:1952-7.
  • Shields JA, Shields CL, Ehya H. Lung cancer diagnosed by fine needle biopsy of the optic disc. Retina. 2001;21:665-6.
  • von Mehren M, Arlen P, Gulley J, Rogatko A, Cooper HS, Meropol NJ, Alpaugh K, Davey M, McLaughlin S, Beard MT, Tsang KY, Schlum J, Weiner LM. The influence of granulocyte macrophage colony stimulating factor and prior chemotherapy on the immunological response to vaccine (ALVA-CEA B7, 1) in patients with metastatic cancer. Clin Cancer Res. 2001;7:1181-91.
  • Wu H, Elitsas R. Malignant nodular hidradenoma in a patient with neurofibromatosis type 1: a case report and review of the literature. Cutis. 2001;68:273-8.
  • Zimmerman RL, Burke M, Young NA, Solomides CC, Bibbo M. Diagnostic value of hepatocyte paraffin 1 antibody to discriminate hepatocellular carcinoma from metastatic carcinoma in fine needle aspirate biopsies of the liver. Cancer. 2001;93:288-91.
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