Camille Ragin, PhD, MPH
Office Phone: 215-728-1148
It is well documented that there are disproportionately higher rates of cancer diagnoses and deaths among Black populations compared to other ethnic groups. This finding is consistent for the Black population in the US as well as developing regions such as the Caribbean and Africa. In addition to socioeconomic factors and access to medical care, environmental exposures, lifestyle and culture are associated with cancer risk. However, the strength of these associations with cancer development may be modified by individual genetic factors.
The ultimate goal of our research program is to use a transdisciplinary approach to address the burden of cancer in Black populations. Through community engagement, we conduct molecular epidemiology research studies in head and neck, lung and prostate cancer by investigating gene x environment interactions that promote racial disparities in cancer.
Through my leadership of the African-Caribbean Cancer Consortium we are able to promote a more holistic approach to better understanding cancer risk and poor outcome among underserved minority populations of African ancestry through research studies conducted locally as well as at a national and global level.Description of research projects
- Jackson MD, Tulloch-Reid MK, McFarlane-Anderson N, Watson A, Seers V, Bennett FI, Egleston B, Ragin C. Complex interaction between serum folate levels and genetic polymorphisms in folate pathway genes: biomarkers of prostate cancer aggressiveness. Genes Nutr. 2012 Sep 25. [Epub ahead of print] PubMed
- Taioli E, Flores-Obando RE, Agalliu I, Blanchet P, Bunker CH, Ferrell RE, Jackson M, Kidd LC, Kolb S, Lavender NA, McFarlane-Anderson N, Morrison SS, Multigner L, Ostrande EA, Park JY, Patrick AL, Rebbeck TR, Romana M, Stanford JL, Ukoli F, Vancleave TT, Zeigler-Johnson CM, Mutetwa B, Ragin C. Multi-institutional prostate cancer study of genetic susceptibility in populations of African descent. Carcinogenesis 2011 Sept; 32(9):1361-5. PubMed
- Ragin CC, Langevin SM, Marzouk M, Grandis J, Taioli E. Determinants of head and neck cancer survival by race. Head Neck. 2011 Aug;33(8):1092-8. PubMed
- Ragin CC, Langevin S, Rubin S, Taioli E. Review of studies on metabolic genes and cancer in populations of African descent. Genet Med. 2010 Jan; 12(1):12-8. PubMed
- Ragin CC, Taioli E, McFarlane-Anderson N, Avery G, Bennett F, Bovell-Benjamin A, Thompson AB, Carrington A, Campbell-Everett L, Ford J, Hennis A, Jackson M, Lake S, Leske MC, Magai C, Nemesure B, Neugut A, Odedina F, Okobia M, Patrick A, Plummer WB, Reams RR, Roberts R, Scott-Hastings S, Sharma S, Wheeler V, Wu SY, Bunker C. African-Caribbean cancer consortium for the study of viral, genetic and environmental cancer risk factors. Infect Agent Cancer. 2007 Sep 24;2:17. PubMed