Faculty Summaries
Jennifer Rhodes, PhD
Jennifer Rhodes, PhD
Assistant Professor
  • Director, Zebrafish Facility
Office Phone: 215-728-3829
Office: R351
Lab: R346

Original Articles

  • Robu ME, Zhang Y, Rhodes J. Rereplication in emi1-Deficient Zebrafish Embryos Occurs through a Cdh1-Mediated Pathway. PLoS One. 2012;7(10):e47658. doi: 10.1371/journal.pone.0047658.
  • Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT. cpsf1 is required for definitive HSC survival in zebrafish. Blood 2011;117(15):3996-4007.
  • Payne EM, Bolli N, Rhodes J, Abdel-Wahab OI, Levine R, Hedvat CV, Stone R, Khanna-Gupta A, Sun H, Kanki JP, Gazda HT, Beggs AH, Cotter FE, Look AT. Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML. Blood 2011;118(4):903-15.
  • Robinson BW, Germano G, Song Y, Abrams J, Scott M, Guariento I, Tiso N, Argenton F, Basso G, Rhodes J, Kanki JP, Look AT, Balice-Gordon RJ, Felix CA. mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in hematopoietic tissues. Br J Haematol 2011;152:307-21.
  • Rhodes J*^, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, Murphy C, Radtke I, Downing JR, Fleming MD, MacConaill LE, Amatruda JF, Gutierrez A, Galinsky I, Stone RM, Ross EA, Pellman DS, Kanki JP, Look AT. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Mol Cell Biol. 2009 Nov;29(21):5911-22. *Corresponding author. ^Cover image selected for publication by journal.
  • Walters K, Dodd M, Mathias J, Gallagher A, Bennin D, Rhodes J, Kanki J, Look AT, Huttenlocher A. Chronic inflammation and muscle degeneration caused by mutation of zebrafish Fad24. Submitted to Dev Dyn September 2008.
  • Mathias JR, Dodd ME, Walters KB, Rhodes J, Kanki JP, Look AT, Huttenlocher A. Live imaging of chronic inflammation caused by mutation of zebrafish Hai1. J Cell Sci. 2007;120(Pt 19):3372-83.
  • Liu TX , Rhodes J, Deng M, Hsu K, Radomska HS, Kanki JP, Tenen DG, Look AT.  Dominant-negative C/ebpa stimulates primitive erythropoiesis in zebrafish. Exp Hematol. 2007 Feb;35(2):230-9.
  • Rhodes J, Hagen A, Hsu K, Deng M, Liu TX, Look AT, Kanki JP. Interplay of pu.1 and gata-1 determines myelo-erythroid progenitor cell fate in zebrafish. Dev Cell. 2005 Jan;8(1):97-108.
  • Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look, AT. The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 2004 Sep 1;104(5):1291-7.
  • Liu T X, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D’Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Dev Cell. 2003 Dec;5:903-14.
  • Liu TX, Zhou Y, Kanki JP, Deng M, Rhodes J, Yang HW, Sheng XM, Zon LI, Look AT. Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies. Proc Natl Acad Sci USA. 2002 Apr 30;99(9):6136-41.
  • Bennett CM, Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. Myelopoiesis in the zebrafish, Danio rerio. Blood. 2001;98:643-51.
  • Rhodes J, York RD, Tara D, Tajinda K, Druker BJ. CrkL functions as a nuclear adaptor and transcriptional activator in Bcr-Abl-expressing cells. Exp Hematol. 2000; 28:305-10.
  • Ozaki K, Oda A, Wakao H, Rhodes J, Druker BJ, Ishida A, Wakui M, Okamoto S, Morita K, Handa M, Komatsu N, Ohashi H, Miyajima A, Ikeda Y. Thrombopoietin induces association of Crkl with STAT5 but not STAT3 in human platelets. Blood. 1998; 92:4652-62.
  • Johnson KR, Smith L, Johnson DK, Rhodes J, Rinchik EM, Thayer M, Lewis EJ. Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome11q13. Genomics. 1996;33:527-31.
  • Zellmer E, Zhang Z, Greco D, Rhodes J, Cassel S, Lewis EJ. A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes. J Neurosci. 1995;15:8109-20

Book chapters

  • Rhodes J, Druker BJ. Jak-STAT signal transduction. In: Zon LI, editor. Hematopoiesis: a developmental approach. New York: Oxford University Press; 2001. p. 269-287.