Medical Leadership

Mary B. Daly, MD, PhD, FACP

Mary Daly
  • Chair, Department of Clinical Genetics
  • Timothy R. Talbot Jr. Chair in Cancer Research

One of Philadelphia Magazine's Top Doctors in Medical Oncology, Mary B. Daly, MD, PhD, is Chair of the Department of Clinical Genetics, and holds the Timothy R. Talbot Jr. Chair in Cancer Research.  Dr. Daly is a national leader in the emerging field of clinical cancer genetics, and is the founder of one of the first cancer risk assessment and counseling programs in the country. 

The Risk Assessment Program at Fox Chase Cancer Center is heavily grounded in research and has contributed to the early observations regarding risk perception and risk-reducing behavior among women with a family history of breast and/or ovarian cancer, and has been instrumental in the development of state-of-the-art cancer risk counseling interventions.  Dr. Daly’s primary areas of research include the epidemiologic and genetic aspects of breast and ovarian cancer, and the translation of this information into effective cancer control approaches. 

As Director of the Ovarian Cancer Consortium for Research and Surveillance (OCCRS), a core facility for the Fox Chase Ovarian SPORE grant, Dr. Daly has initiated studies of ovarian cancer screening modalities, quality of life after prophylactic surgery and serum biomarkers of breast and ovarian cancer risk.  As Principal Investigator of the Cooperative Family Registry for Breast Cancer Studies, she is collaborating with institutions worldwide to study the patterns of familial breast and ovarian cancer, gene-environment interactions, and the development of novel, genetic-based therapeutic and preventive strategies.  She is a member of the Cancer Control Committee of the Gynecologic Oncology Group (GOG), and chairs the Hereditary Breast and Ovarian Cancer Risk Panel for the National Comprehensive Cancer Network (NCCN).  Dr. Daly is a leader in the design of educational programs in cancer genetics and cancer risk for both high risk individuals and for their health care providers.  She serves as the Principal Investigator of the NSABP breast cancer prevention trials (P1 and STAR).  She is the Past President of the American Society of Preventive Oncology.